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院内心搏骤停特征、不同科室心血管疾病患者心搏骤停病因和结局:一项回顾性研究。

In-hospital cardiac arrest characteristics, causes and outcomes in patients with cardiovascular disease across different departments: a retrospective study.

机构信息

Department of Anesthesiology, Fuwai Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, No.167 North Lishi Road, Xicheng District, Beijing, China.

Department of Medical Intensive Care Units, Fuwai Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, No.167 North Lishi Road, Xicheng District, Beijing, China.

出版信息

BMC Cardiovasc Disord. 2024 Sep 6;24(1):475. doi: 10.1186/s12872-024-04152-y.

Abstract

BACKGROUND

Cardiac etiologies arrest accounts for almost half of all in-hospital cardiac arrest (IHCA), and previous studies have shown that the location of IHCA is an important factor affecting patient outcomes. The aim was to compare the characteristics, causes and outcomes of cardiovascular disease in patients suffering IHCA from different departments of Fuwai hospital in Beijing, China.

METHODS

We included patients who were resuscitated after IHCA at Fuwai hospital between March 2017 and August 2022. We categorized the departments where cardiac arrest occurred as cardiac surgical or non-surgical units. Independent predictors of in-hospital survival were assessed by logistic regression.

RESULTS

A total of 119 patients with IHCA were analysed, 58 (48.7%) patients with cardiac arrest were in non-surgical units, and 61 (51.3%) were in cardiac surgical units. In non-surgical units, acute myocardial infarction/cardiogenic shock (48.3%) was the main cause of IHCA. Cardiac arrest in cardiac surgical units occurred mainly in patients who were planning or had undergone complex aortic replacement (32.8%). Shockable rhythms (ventricular fibrillation/ventricular tachycardia) were observed in approximately one-third of all initial rhythms in both units. Patients who suffered cardiac arrest in cardiac surgical units were more likely to return to spontaneous circulation (59.0% vs. 24.1%) and survive to hospital discharge (40.0% vs. 10.2%). On multivariable regression analysis, IHCA in cardiac surgical units (OR 5.39, 95% CI 1.90-15.26) and a shorter duration of resuscitation efforts (≤ 30 min) (OR 6.76, 95% CI 2.27-20.09) were associated with greater survival rate at discharge.

CONCLUSION

IHCA occurring in cardiac surgical units and a duration of resuscitation efforts less than 30 min were associated with potentially increased rates of survival to discharge.

摘要

背景

心脏病因导致的心脏骤停(IHCA)占所有院内心脏骤停的近一半,既往研究表明,IHCA 的发生地点是影响患者预后的重要因素。本研究旨在比较中国北京阜外医院不同科室发生 IHCA 的患者的特征、病因和结局。

方法

我们纳入了 2017 年 3 月至 2022 年 8 月期间在阜外医院接受 IHCA 复苏的患者。我们将发生心脏骤停的科室分为心脏外科或非心脏外科单元。采用逻辑回归评估院内生存的独立预测因素。

结果

共分析了 119 例 IHCA 患者,58 例(48.7%)心脏骤停患者在非心脏外科单元,61 例(51.3%)在心脏外科单元。在非心脏外科单元,急性心肌梗死/心源性休克(48.3%)是 IHCA 的主要病因。心脏外科单元的心脏骤停主要发生在计划或已接受复杂主动脉置换术的患者(32.8%)中。两个单元中约三分之一的初始节律为可除颤节律(室颤/室速)。在心脏外科单元发生心脏骤停的患者更有可能恢复自主循环(59.0%比 24.1%)和存活至出院(40.0%比 10.2%)。多变量回归分析显示,心脏外科单元的 IHCA(OR 5.39,95%CI 1.90-15.26)和较短的复苏时间(≤30 分钟)(OR 6.76,95%CI 2.27-20.09)与出院时的生存率更高相关。

结论

心脏外科单元发生的 IHCA 和复苏时间小于 30 分钟与出院时的生存率增加有关。

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