Fu Zi-Yue, Li Da-Peng, Shen Chuan-Lu, Wang Jian-Peng, Han Yan-Xun, Chen Shan-Wen, Ding Zhao, Zhang Lei, Liang Bing-Yu, Yin Si-Yue, Yang Yi-Pin, Zhang Yu-Lin, Li Yan, Liu Ye-Hai, Pan Hai-Feng, Wu Kai-Le, Liu Yu-Chen
Department of Otolaryngology, Head and Neck Surgery, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.
Department of Otolaryngology, Head and Neck Surgery, The Affiliated Bozhou Hospital of Anhui Medical University, Bozhou, Anhui, China.
Laryngoscope. 2025 Jan;135(1):34-44. doi: 10.1002/lary.31750. Epub 2024 Sep 7.
The purpose of this study was to assess the diagnostic performance of narrow-band imaging (NBI) in monitoring patients with head and neck carcinomas posttreatment and to compare it with that of white light endoscopy (WLE).
PubMed, Embase, Web of Science (WOS), Cochrane Library, China Biology Medicine disc (CBM disc), China National Knowledge Internet (CNKI), Wanfang Data, China Science and Technology Journal Database (CSTJ), Chinese Clinical Trial Register.
Using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA), literature published before July 2024 was searched. Patients who underwent surgery, radiotherapy (RT), or chemo-RT for head and neck carcinomas with posttreatment follow-up using NBI were analyzed. The main outcomes were sensitivity, specificity, and diagnostic odds ratio (DOR) for NBI and WLE in posttreatment follow-up.
The sensitivity, specificity, and DOR for NBI and WLE in posttreatment follow-up for head and neck carcinomas were 95% (95% confidence interval [CI]: 88%-98%), 96% (95% CI: 92%-98%), 433 (95% CI: 120-1560) and 72% (95% CI: 49%-87%), 72% (95% CI: 4%-99%), 7 (95% CI: 0-191). Additionally, the area under the curve (AUC) values for NBI and WLE were 0.99 (95% CI: 0.97-0.99) and 0.75 (95% CI: 0.71-0.79), respectively. The number of lesions and patients, treatment modality, follow-up time, disease, and endoscopic system might be sources of heterogeneity.
Compared to WLE, NBI demonstrated superior diagnostic performance in follow-up patients with head and neck carcinoma posttreatment. NBI offers technical support and a clinical foundation for early detection of head and neck carcinoma recurrence.
NA Laryngoscope, 135:34-44, 2025.
本研究旨在评估窄带成像（NBI）在监测头颈部癌患者治疗后的诊断性能，并将其与白光内镜检查（WLE）进行比较。
PubMed、Embase、科学引文索引（WOS）、考克兰图书馆、中国生物医学文献数据库（CBM disc）、中国知网（CNKI）、万方数据、中国科技期刊数据库（CSTJ）、中国临床试验注册中心。
采用系统评价和Meta分析的首选报告项目（PRISMA），检索2024年7月之前发表的文献。分析接受手术、放疗（RT）或放化疗治疗头颈部癌并使用NBI进行治疗后随访的患者。主要结局是NBI和WLE在治疗后随访中的敏感性、特异性和诊断比值比（DOR）。
头颈部癌治疗后随访中NBI和WLE的敏感性、特异性和DOR分别为95%（95%置信区间[CI]：88%-98%）、96%（95%CI：92%-98%）、433（95%CI：120-1560）和72%（95%CI：49%-87%）、72%（95%CI：4%-99%）、7（95%CI：0-191）。此外，NBI和WLE的曲线下面积（AUC）值分别为0.99（95%CI：0.97-0.99）和0.75（95%CI：0.71-0.79）。病变数量和患者数量、治疗方式、随访时间、疾病和内镜系统可能是异质性的来源。
与WLE相比，NBI在头颈部癌治疗后随访患者中表现出更好的诊断性能。NBI为头颈部癌复发的早期检测提供了技术支持和临床基础。
NA 喉镜，135:34-44，2025年。
