Szeps Abel, Suarez Juan Manuel, Torres Rodrigo, Iribarren Rafael
Hospital Posadas, Buenos Aires, Argentina.
+Ophthalmology, Buenos Aires, Argentina.
Graefes Arch Clin Exp Ophthalmol. 2025 Feb;263(2):581-588. doi: 10.1007/s00417-024-06633-4. Epub 2024 Sep 7.
To evaluate changes in choroidal thickness in presbyopes, when reading with regular glasses versus choroidal control glasses, in patients with or without Age-Related Macular Degeneration (AMD).
This was a pilot study on short-term axial length (AL) in 33 eyes of 24 presbyopic patients aged 60 to 80 years, assigned to two age-matched groups, with or without AMD. About them, changes in choroidal thickness were evaluated with ocular biometry through indirect measurements of axial length at baseline, after 20' of reading with conventional lenses, and after another 20' of reading with peripheral hyperopic defocus glasses. The differences in axial length between the three different times were analyzed.
In presbyopes without AMD there was a significant axial length shortening of -13.44 microns in the first conventional reading period, which was reversed by 90% with hyperopic defocus lenses, recovering + 12.11 microns by axial lengthening (choroidal thinning, p = 0.03). In patients with AMD, axial shortening was significantly greater than controls, -23.86 microns with conventional lenses (p < 0.001) and they, also increased their axial length with defocus, although this response was smaller in proportion (+ 15.52 microns).
Reading with positive lenses produces myopic defocus and choroidal thickening in presbyopes with and without AMD but was significantly greater in the latter. Glasses with Choroidal Control Technology reduced thickening during reading.
What is known • Presbyopia spectacles for near produce myopic defocus and choroidal thickening. What is new • There are differences in choroidal thickening during reading between normal subjects and those with age related macular degeneration. • Spectacles with Defocus Choroidal Control Technology reduce choroidal thickening during reading in presbyopes.
评估在患有或未患有年龄相关性黄斑变性（AMD）的老花眼患者中，佩戴普通眼镜阅读与佩戴脉络膜控制眼镜阅读时脉络膜厚度的变化。
这是一项针对24名年龄在60至80岁的老花眼患者的33只眼睛进行的短期眼轴长度（AL）的初步研究，这些患者被分为两个年龄匹配组，分别患有或未患有AMD。对他们而言，通过间接测量基线时的眼轴长度、佩戴传统镜片阅读20分钟后以及再佩戴周边远视性离焦眼镜阅读20分钟后的眼轴长度，利用眼部生物测量法评估脉络膜厚度的变化。分析了三个不同时间点眼轴长度的差异。
在未患有AMD的老花眼患者中，在第一个传统阅读阶段眼轴长度显著缩短了-13.44微米，而佩戴远视性离焦镜片后90%得到逆转，通过眼轴延长恢复了+12.11微米（脉络膜变薄，p = 0.03）。在患有AMD的患者中，眼轴缩短显著大于对照组，佩戴传统镜片时为-23.86微米（p < 0.001），并且他们在离焦时眼轴长度也增加了，尽管这种反应的比例较小（+15.52微米）。
佩戴正镜片阅读会在患有和未患有AMD的老花眼患者中产生近视性离焦和脉络膜增厚，但在后者中更为显著。采用脉络膜控制技术的眼镜可减少阅读期间的增厚。
已知内容 • 用于看近的老花眼镜会产生近视性离焦和脉络膜增厚。新内容 • 正常受试者与患有年龄相关性黄斑变性的受试者在阅读期间脉络膜增厚存在差异。 • 采用离焦脉络膜控制技术的眼镜可减少老花眼患者阅读期间的脉络膜增厚。
