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马来西亚老龄化与退休研究中的生活目的与认知功能

Purpose in Life and Cognitive Function in the Malaysian Ageing and Retirement Study.

作者信息

Sutin Angelina R, Mansor Norma, Luchetti Martina, Stephan Yannick, Terracciano Antonio

机构信息

Department of Behavioral Sciences and Social Medicine, Florida State University College of Medicine, Tallahassee, FL, USA.

Social Wellbeing Research Centre, Universiti Malaya, Kuala Lumpur, Malaysia.

出版信息

Clin Gerontol. 2024 Sep 8:1-10. doi: 10.1080/07317115.2024.2400283.

Abstract

OBJECTIVES

Evidence for the association between purpose in life and cognitive health is primarily from North American and European samples. This study evaluates this association in a large sample from Malaysia, an upper-middle-income country in Southeast Asia.

METHODS

Participants ( = 5,579) from the Malaysian Ageing and Retirement Study reported on their purpose in life and subjective memory and were administered tasks that measured episodic memory, verbal fluency, and overall cognitive function.

RESULTS

Purpose was associated with better subjective memory (β=.13), episodic memory (β=.06), verbal fluency (β=.12), and overall cognitive function (β=.07) (ps < .001). The associations were similar across sex and retirement status; purpose was more strongly related to subjective memory and overall cognitive function among older participants. Behavioral/social factors accounted for up to one-third of the associations, but all associations remained statistically significant.

CONCLUSIONS

The positive association between purpose and cognition generalizes to a middle-income country in Southeast Asia. Similar to Western samples, behavioral and social factors accounted for part but not all the association. More research is needed in lower- and other middle-income countries to fully evaluate generalizability.

CLINICAL IMPLICATIONS

Purpose may help support healthier cognitive aging across diverse populations and be a useful target to improve cognitive aging outcomes.

摘要

目的

关于生活目标与认知健康之间关联的证据主要来自北美和欧洲的样本。本研究在来自马来西亚(东南亚的一个中高收入国家)的大样本中评估这种关联。

方法

马来西亚老龄化与退休研究的参与者(n = 5579)报告了他们的生活目标和主观记忆情况,并接受了测量情景记忆、语言流畅性和整体认知功能的任务。

结果

生活目标与更好的主观记忆(β = 0.13)、情景记忆(β = 0.06)、语言流畅性(β = 0.12)和整体认知功能(β = 0.07)相关(p < 0.001)。这些关联在性别和退休状态方面相似;在老年参与者中,生活目标与主观记忆和整体认知功能的关系更强。行为/社会因素占这些关联的三分之一,但所有关联在统计学上仍具有显著性。

结论

生活目标与认知之间的正相关关系在东南亚的一个中高收入国家也成立。与西方样本类似,行为和社会因素占部分而非全部关联。需要在低收入和其他中高收入国家开展更多研究以充分评估其普遍性。

临床意义

生活目标可能有助于支持不同人群更健康的认知老化,并且是改善认知老化结果的一个有用靶点。

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