Kashanian Maryam, Khalili Pantea, Jaliliyan Ali, Baradaran Hamid Reza
Department of Obstetrics & Gynecology, Akbarabadi Teaching Hospital, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Department of Epidemiology, School of Public Health, Iran University of Medical Sciences, Tehran, Iran.
Int J Gynaecol Obstet. 2025 Feb;168(2):735-742. doi: 10.1002/ijgo.15901. Epub 2024 Sep 7.
To assess variations in the presentation and clinical implications of pre-eclampsia between Iranian and Afghan mothers at a maternity center in Tehran.
We conducted a cross-sectional study of Iranian and Afghan mothers diagnosed with pre-eclampsia. Data were collected from March 2021 to February 2023 at a maternity center in Tehran, Iran. Demographic information, clinical characteristics, and laboratory findings were extracted from medical records. Statistical analyses were employed to compare differences between Iranian and Afghan mothers, including Mann-Whitney U, Pearson χ tests, and logistic regression models.
We included 822 pregnant women with pre-eclampsia, predominantly Iranian (75.5%) and Afghan (24.5%). Regarding the multivariate logistic regression model, Iranian mothers were older, with a higher proportion over 35 years. Although Afghan mothers showed higher gravidity counts and greater gestational ages at delivery, they had lower rates of hypothyroidism. Iranian women were more often categorized as obese than Afghan women, and the difference was statistically significant. Serum levels of alkaline phosphatase were significantly greater in Afghan women.
Pre-eclampsia poses significant maternal health risks, especially among Afghan refugees in Iran. Variances in age, gravidity, and hypothyroidism prevalence highlight the need for tailored healthcare strategies. Addressing cultural barriers and implementing targeted interventions can improve maternal and fetal outcomes in these populations.
评估伊朗和阿富汗母亲在德黑兰一家妇产中心子痫前期的临床表现及临床意义的差异。
我们对诊断为子痫前期的伊朗和阿富汗母亲进行了一项横断面研究。数据于2021年3月至2023年2月在伊朗德黑兰的一家妇产中心收集。从医疗记录中提取人口统计学信息、临床特征和实验室检查结果。采用统计分析方法比较伊朗和阿富汗母亲之间的差异，包括曼-惠特尼U检验、皮尔逊χ检验和逻辑回归模型。
我们纳入了822例子痫前期孕妇，其中主要是伊朗人（75.5%）和阿富汗人（24.5%）。关于多变量逻辑回归模型，伊朗母亲年龄较大，35岁以上的比例较高。虽然阿富汗母亲的妊娠次数较多，分娩时孕周较大，但她们的甲状腺功能减退率较低。伊朗女性比阿富汗女性更常被归类为肥胖，且差异具有统计学意义。阿富汗女性血清碱性磷酸酶水平显著更高。
子痫前期对孕产妇健康构成重大风险，尤其是在伊朗的阿富汗难民中。年龄、妊娠次数和甲状腺功能减退患病率的差异凸显了制定针对性医疗保健策略的必要性。消除文化障碍并实施有针对性的干预措施可改善这些人群的母婴结局。
