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Tissue levels of Alternaria allergen Alt a 1 reflect recurrence of refractory airway diseases.

作者信息

Miyabe Yui, Abe Tomoe, Yamada Toshiki, Endo Tentaro, Kawasaki Yohei, Suzuki Shinsuke, Arima Misaki, Ueki Shigeharu, Yamada Takechiyo

机构信息

Department of Otorhinolaryngology, Head and Neck Surgery, Graduate School of Medicine, Akita University, Akita, Japan.

Department of General Internal Medicine and Clinical Laboratory Medicine, Graduate School of Medicine, Akita University, Akita, Japan.

出版信息

Allergy. 2025 Feb;80(2):587-589. doi: 10.1111/all.16294. Epub 2024 Sep 7.

DOI:10.1111/all.16294
PMID:39244710
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11804301/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b2d7/11804301/b986d6e45c60/ALL-80-587-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b2d7/11804301/ccfbceecf4db/ALL-80-587-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b2d7/11804301/b986d6e45c60/ALL-80-587-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b2d7/11804301/ccfbceecf4db/ALL-80-587-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b2d7/11804301/b986d6e45c60/ALL-80-587-g001.jpg

相似文献

1
Tissue levels of Alternaria allergen Alt a 1 reflect recurrence of refractory airway diseases.链格孢过敏原Alt a 1的组织水平反映难治性气道疾病的复发情况。
Allergy. 2025 Feb;80(2):587-589. doi: 10.1111/all.16294. Epub 2024 Sep 7.
2
Correction to "Tissue Levels of Alternaria Allergen Alt a 1 Reflect Recurrence of Refractory Airway Diseases".《“链格孢过敏原Alt a 1的组织水平反映难治性气道疾病的复发”的更正》
Allergy. 2025 Jun;80(6):1821. doi: 10.1111/all.16574. Epub 2025 May 2.
3
Monoclonal antibody-based assay for Alt a1, a major Alternaria allergen.
Ann Allergy Asthma Immunol. 1998 Jul;81(1):59-64. doi: 10.1016/s1081-1206(10)63110-9.
4
Northern blot identification of mRNA containing sequence for protein allergen, Alt a1, in eight strains of Alternaria alternata.通过Northern印迹法鉴定八株链格孢菌中含有蛋白质过敏原Alt a1序列的mRNA。
Ann Allergy Asthma Immunol. 1998 Jun;80(6):471-5. doi: 10.1016/S1081-1206(10)63069-4.
5
Alternaria extract activates autophagy that induces IL-18 release from airway epithelial cells.链格孢菌提取物激活自噬，从而诱导气道上皮细胞释放白细胞介素-18。
Biochem Biophys Res Commun. 2015 Sep 4;464(4):969-974. doi: 10.1016/j.bbrc.2015.05.076. Epub 2015 May 30.
6
Spore germination increases allergen release from Alternaria.孢子萌发会增加链格孢属真菌的过敏原释放量。
J Allergy Clin Immunol. 2001 Feb;107(2):388-90. doi: 10.1067/mai.2001.112602.
7
Production profile of the major allergen Alt a 1 in Alternaria alternata cultures.链格孢菌培养物中主要过敏原Alt a 1的生产概况。
Ann Allergy Asthma Immunol. 2004 Dec;93(6):589-93. doi: 10.1016/S1081-1206(10)61268-9.
8
Alternaria induces airway epithelial cytokine expression independent of protease-activated receptor.交链格孢诱导气道上皮细胞细胞因子表达不依赖蛋白酶激活受体。
Respirology. 2020 May;25(5):502-510. doi: 10.1111/resp.13675. Epub 2019 Aug 20.
9
Identifying key environmental factors to model Alt a 1 airborne allergen presence and variation.识别关键环境因素，以建立模式来模拟 Alt a 1 空气过敏原的存在和变化。
Sci Total Environ. 2024 Mar 20;917:170597. doi: 10.1016/j.scitotenv.2024.170597. Epub 2024 Feb 1.
10
Predominance of the major allergen (Alt a I) in Alternaria sensitized patients.
Clin Exp Allergy. 1993 Mar;23(3):211-8. doi: 10.1111/j.1365-2222.1993.tb00884.x.

本文引用的文献

1
Allergen-induced DNA release by the airway epithelium amplifies type 2 immunity.气道上皮细胞诱导的过敏原 DNA 释放可放大 2 型免疫。
J Allergy Clin Immunol. 2023 Feb;151(2):494-508.e6. doi: 10.1016/j.jaci.2022.09.034. Epub 2022 Oct 25.
2
Galectin-10 as a Potential Biomarker for Eosinophilic Diseases.半乳糖凝集素-10 作为嗜酸性疾病的潜在生物标志物。
Biomolecules. 2022 Sep 27;12(10):1385. doi: 10.3390/biom12101385.
3
Quantification of Aspergillus fumigatus antigen Asp f 1 in airway tissue and allergic inflammation.气道组织中烟曲霉抗原Asp f 1的定量分析与变应性炎症
Allergy. 2022 Oct;77(10):3154-3156. doi: 10.1111/all.15428. Epub 2022 Jul 15.
4
as an Inducer of Allergic Sensitization.作为过敏致敏的诱导剂。
J Fungi (Basel). 2021 Oct 7;7(10):838. doi: 10.3390/jof7100838.
5
An overview of possible pathogenesis mechanisms of Alternaria alternata in chronic rhinosinusitis and nasal polyposis.变应性曲霉菌病在慢性鼻-鼻窦炎和鼻息肉发病机制中的作用概述。
Microb Pathog. 2021 Jun;155:104905. doi: 10.1016/j.micpath.2021.104905. Epub 2021 Apr 27.
6
Pyruvate kinase M2 in lung APCs regulates Alternaria-induced airway inflammation.肺 APCs 中的丙酮酸激酶 M2 调节交链格孢菌诱导的气道炎症。
Immunobiology. 2020 Jul;225(4):151956. doi: 10.1016/j.imbio.2020.151956. Epub 2020 May 30.
7
Double-blind, randomized, placebo-controlled trial of allergen-specific immunotherapy with the major allergen Alt a 1.双盲、随机、安慰剂对照的过敏原特异性免疫治疗与主要过敏原 Alt a 1 的试验
J Allergy Clin Immunol. 2019 Jul;144(1):216-223.e3. doi: 10.1016/j.jaci.2019.02.029. Epub 2019 Mar 14.
8
STAT6 Regulates the Development of Eosinophilic versus Neutrophilic Asthma in Response to Alternaria alternata.信号转导和转录激活因子6（STAT6）在应对链格孢菌时调节嗜酸性粒细胞性哮喘与中性粒细胞性哮喘的发展。
J Immunol. 2016 Dec 15;197(12):4541-4551. doi: 10.4049/jimmunol.1600007. Epub 2016 Nov 4.
9
Wheezing and bronchial hyper-responsiveness in early childhood as predictors of newly diagnosed asthma in early adulthood: a longitudinal birth-cohort study.儿童期喘息和支气管高反应性作为成年早期新诊断哮喘的预测因素：一项出生队列纵向研究。
Lancet. 2008 Sep 20;372(9643):1058-64. doi: 10.1016/S0140-6736(08)61447-6.
10
Exposure to an aeroallergen as a possible precipitating factor in respiratory arrest in young patients with asthma.暴露于空气变应原作为哮喘年轻患者呼吸骤停的一个可能诱发因素。
N Engl J Med. 1991 Feb 7;324(6):359-63. doi: 10.1056/NEJM199102073240602.