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生理屈曲包裹法和口部运动干预对改善新生儿重症监护病房早产儿经口喂养能力的有效性：一项随机对照试验。

Effectiveness of physiological flexion swaddling and oromotor interventions in improving preterm infants' oral feeding ability in the NICU: a randomized controlled trial.

作者信息

Wahyuni Luh K, Mangunatmadja Irawan, Kaban Risma K, Rachmawati Elvie Zulka K, Wardhani Rizky K, Laksmitasari Budiati, Nugraha Boya

机构信息

Faculty of Medicine Universitas Indonesia - Dr. Cipto Mangunkusumo Hospital, Physical Medicine and Rehabilitation Department, Jakarta, Indonesia.

Faculty of Medicine Universitas Indonesia - Dr. Cipto Mangunkusumo Hospital, Department of Child Health, Jakarta, Indonesia.

出版信息

J Pediatr (Rio J). 2025 Jan-Feb;101(1):46-53. doi: 10.1016/j.jped.2024.06.014. Epub 2024 Sep 5.

DOI:10.1016/j.jped.2024.06.014
PMID:39245236
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11763616/
Abstract

OBJECTIVE

This study aimed to prove the effectiveness of physiological flexion swaddling and oromotor interventions in terms of the duration needed to achieve the oral feeding ability of preterm infants in the NICU.

METHODS

A randomized clinical trial in five Neonatal intensive care units (NICU) was performed involving 70 preterm infants born at 28-34 weeks gestational age. Participants were allocated to 1) the experimental group (n = 39) received physiological flexion swaddling and oromotor interventions, and 2) the control group (n = 31) received conventional swaddling and oromotor interventions. Mann-Whitney U analysis was used to determine the effectiveness of each group according to the duration needed to achieve oral feeding ability, while Kaplan-Meier survival analysis was applied to compare the duration of both groups.

RESULTS

The experimental group had a significantly shorter duration in achieving oral feeding ability [4 (1-15) vs. 7 (2-22) days; p = 0.02]. The Kaplan-Meier survival curve analysis showed that infants in the experimental group achieved full oral feeding ability earlier than those in the control group (15 vs. 22 days).

CONCLUSIONS

Physiological flexion swaddling and oromotor interventions have been proven to be effective in shortening the number of days needed to achieve the oral feeding ability of preterm infants in the NICU.

摘要

目的

本研究旨在证明生理屈曲襁褓法和口腔运动干预在缩短新生儿重症监护病房（NICU）中早产儿实现经口喂养能力所需时间方面的有效性。

方法

在五个新生儿重症监护病房进行了一项随机临床试验，纳入了70名孕周为28 - 34周的早产儿。参与者被分为两组：1）实验组（n = 39）接受生理屈曲襁褓法和口腔运动干预；2）对照组（n = 31）接受传统襁褓法和口腔运动干预。采用曼-惠特尼U分析根据实现经口喂养能力所需时间来确定每组的有效性，同时应用Kaplan-Meier生存分析来比较两组的时间。

结果

实验组在实现经口喂养能力方面的时间明显更短[4（1 - 15）天 vs. 7（2 - 22）天；p = 0.02]。Kaplan-Meier生存曲线分析表明，实验组婴儿比对照组婴儿更早实现完全经口喂养能力（15天 vs. 22天）。

结论

生理屈曲襁褓法和口腔运动干预已被证明在缩短NICU中早产儿实现经口喂养能力所需天数方面是有效的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a3cc/11763616/76eeb7ff6b50/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a3cc/11763616/a5e5e3036243/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a3cc/11763616/3fe31a89f283/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a3cc/11763616/76eeb7ff6b50/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a3cc/11763616/a5e5e3036243/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a3cc/11763616/3fe31a89f283/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a3cc/11763616/76eeb7ff6b50/gr3.jpg

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本文引用的文献

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Effectiveness of Oral Sensory-Motor Stimulation in Premature Infants in the Neonatal Intensive Care Unit (NICU) Systematic Review.新生儿重症监护病房（NICU）中口腔感觉运动刺激对早产儿的有效性：系统评价
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Principles of Neurorehabilitation After Stroke Based on Motor Learning and Brain Plasticity Mechanisms.
基于运动学习和脑可塑性机制的脑卒中后神经康复原则
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Effect of oral stimulation on feeding performance and weight gain in preterm neonates: a randomised controlled trial.口腔刺激对早产儿喂养性能和体重增加的影响：一项随机对照试验。
Paediatr Int Child Health. 2018 Aug;38(3):181-186. doi: 10.1080/20469047.2018.1435172. Epub 2018 Feb 19.
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Oral stimulation for promoting oral feeding in preterm infants.口腔刺激促进早产儿经口喂养
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Instruments for assessing readiness to commence suck feeds in preterm infants: effects on time to establish full oral feeding and duration of hospitalisation.评估早产儿开始吸吮喂养准备情况的工具：对建立完全经口喂养时间和住院时长的影响。
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