Department of Medical Mycology, Institute of Dermatology and Hospital for Skin Diseases, Chinese Academy of Medical Sciences & Peking Union Medical College, Nanjing, China.
Department of Dermatology and Venereology, Peking University First Hospital, Beijing, China.
Mycoses. 2024 Sep;67(9):e13785. doi: 10.1111/myc.13785.
Antifungal-resistant dermatophytes (ARD) infection is a hotspot issue in clinical microbiology and the dermatology field. Trichophyton indotineae as the dominant species of dermatophyte with terbinafine-resistance or multidrug resistance, is easy to be missed detection clinically, which brings severe challenges to diagnosis and treatment. ARD infection cases have emerged in China, and it predicts a risk of transmission among human. Based on the existing medical evidence and research data, the Mycology Group of Combination of Traditional and Western Medicine Dermatology and Chinese Antifungal⁃Resistant Dermatophytoses Expert Consensus Group organized experts to make consensus on the management of the infection. Here, the consensus formulated diagnosis and treatment recommendations, to raise attention to dermatophytes drug resistance problem, and expect to provide reference information for the clinical diagnosis, treatment, prevention and control.
抗真菌药物耐药的皮肤癣菌(ARD)感染是临床微生物学和皮肤科领域的热点问题。特比萘芬耐药或多药耐药的优势菌种堇毛癣菌在临床上容易被漏检,给诊断和治疗带来了严峻挑战。ARD 感染在中国已经出现,且有在人群中传播的风险。基于现有的医学证据和研究数据,中西医结合皮肤病学真菌学组和中国抗真菌耐药皮肤癣菌专家共识组组织专家就感染的管理达成共识。在这里,制定了共识诊断和治疗建议,以引起对皮肤癣菌耐药问题的关注,并期望为临床诊断、治疗、预防和控制提供参考信息。