Emerg Infect Dis. 2022 Jan;28(1):229-233. doi: 10.3201/eid2801.210883.
Extensive dermatophytosis caused by terbinafine-resistant Trichophyton indotineae harboring Phe397Leu and Leu393Ser substitutions in the squalene epoxidase enzyme was diagnosed in France. Analysis of internal transcribed spacer sequences revealed the wide spread of this species in Asia and Europe. Detection of T. indotineae in animals suggests their possible role as reservoirs.
法国诊断出一例由特比萘芬耐药的堇毛癣菌引起的广泛皮肤癣病，该菌的角鲨烯环氧化酶基因中存在 Phe397Leu 和 Leu393Ser 取代。内部转录间隔区序列分析显示该物种在亚洲和欧洲广泛传播。在动物中检测到堇毛癣菌表明它们可能作为储主的作用。
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