Department of Research, Training and Development, Assisting Deputyship for Primary Health Care, Ministry of Health, Riyadh, Saudi Arabia.
Department of Biomedical Sciences, College of Veterinary Medicine, King Faisal University, Al-Ahsa, Saudi Arabia.
Expert Rev Endocrinol Metab. 2024 Nov;19(6):513-522. doi: 10.1080/17446651.2024.2400706. Epub 2024 Sep 8.
According to previous reports, very high percentages of individuals in Saudi Arabia are undiagnosed for type 2 diabetes mellitus (T2DM). Despite conducting several screening and awareness campaigns, these efforts lacked full accessibility and consumed extensive human and material resources. Thus, developing machine learning (ML) models could enhance the population-based screening process. The study aims to compare a newly developed ML model's outcomes with the validated American Diabetes Association's (ADA) risk assessment regarding predicting people with high risk for T2DM.
Patients' age, gender, and risk factors that were obtained from the National Health Information Center's dataset were used to build and train the ML model. To evaluate the developed ML model, an external validation study was conducted in three primary health care centers. A random sample ( = 3400) was selected from the non-diabetic individuals.
The results showed the plotted data of sensitivity/100-specificity represented in the Receiver Operating Characteristic (ROC) curve with an AROC value of 0.803, 95% CI: 0.779-0.826.
The current study reveals a new ML model proposed for population-level classification that can be an adequate tool for identifying those at high risk of T2DM or who already have T2DM but have not been diagnosed.
根据以往的报告,沙特阿拉伯有非常高比例的人未被诊断出 2 型糖尿病(T2DM)。尽管开展了多次筛查和宣传活动,但这些努力缺乏全面的可及性,耗费了大量的人力和物力资源。因此,开发机器学习(ML)模型可以增强基于人群的筛查过程。本研究旨在比较新开发的 ML 模型与经过验证的美国糖尿病协会(ADA)风险评估在预测 T2DM 高危人群方面的结果。
使用从国家健康信息中心数据集获得的患者年龄、性别和风险因素来构建和训练 ML 模型。为了评估开发的 ML 模型,在三个初级保健中心进行了外部验证研究。从非糖尿病个体中随机抽取了一个样本( = 3400)。
结果显示,在接收器操作特征(ROC)曲线上以灵敏度/100-特异性绘制的数据,其曲线下面积(AUC)值为 0.803,95%置信区间(CI)为 0.779-0.826。
本研究揭示了一种新的用于人群分类的 ML 模型,它可以作为一种识别 T2DM 高危人群或已经患有 T2DM 但尚未被诊断的工具。