Rodríguez Gabriel, Azariah Abana, Quoilin Melanie, Garcia-Garcia Ricardo, Ladera Fernandez Valentina, Boake Corwin, Meurgue Ritter Alexandra, Gonzalez Arlen
Stroke & Brain Injury Program, TIRR Memorial Hermann Texas Medical Center, Houston, TX, USA.
Adjunct Professor, The University of Texas Health Science Center, Houston, TX, USA.
Brain Inj. 2025 Jan 2;39(1):35-38. doi: 10.1080/02699052.2024.2396018. Epub 2024 Sep 8.
GAAB Syndrome was recently discovered and coined by Rodríguez, Azariah, Ritter, et al.. (2024). It is characterized by bifrontal brain injury, visual pathway damage involving bilateral enucleation, generalized and visual anosognosia and lack of emotional processing with visual anosognosia being more prominent in the clinical presentation of the patient given the context of bilateral enucleation. The syndrome was not explained by delirium nor by amnesia, not either by multiple shunt adjustments or psychological denial.
To describe the clinical presentation and syndrome length of the patient one year after injury. Results show that most of the syndrome symptoms are resolved after nine months, with just visual anosognosia not resolving completely. The patient improved cognitively as shown by the same tests one year later.
GAAB综合征最近由罗德里格斯、阿扎里亚、里特等人(2024年)发现并命名。其特征为双侧额叶脑损伤、涉及双侧眼球摘除的视觉通路损伤、全身性和视觉失认症以及缺乏情感处理,鉴于双侧眼球摘除的情况,视觉失认症在患者的临床表现中更为突出。该综合征既不能用谵妄来解释,也不能用失忆来解释,也不能用多次分流调整或心理否认来解释。
描述患者受伤一年后的临床表现和综合征持续时间。结果显示,九个月后大多数综合征症状得到缓解,只有视觉失认症未完全缓解。一年后的相同测试表明患者认知功能有所改善。