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在阿布扎比的一家三级医院中儿童维生素 D 缺乏症及相关人口统计学危险因素分析。

Vitamin D deficiency and associated demographic risk factors in children at a tertiary hospital in Abu Dhabi.

机构信息

Department of Pediatrics, Sheikh Shakhbout Medical City, Abu Dhabi, UAE.

Pediatrics Department, Khalifa University, Abu Dhabi, UAE.

出版信息

Paediatr Int Child Health. 2024 Sep-Nov;44(3-4):105-110. doi: 10.1080/20469047.2024.2396714. Epub 2024 Sep 8.

DOI:10.1080/20469047.2024.2396714
PMID:39246017
Abstract

BACKGROUND

Despite ample sunshine, vitamin D deficiency continues to be prevalent in the Middle East. This pilot study aimed to identify the rate of vitamin D deficiency at a tertiary hospital in Abu Dhabi and to identify the associated risk factors in children and adolescents.

METHODOLOGY

A retrospective observational study was conducted using electronic medical records of paediatric patients who underwent 25-hydroxyvitamin D testing at Sheikh Shakhbout Medical City, Abu Dhabi between 1 January 2020 and 31 December 2021. Data on age, gender, ethnicity, weight, body mass index and other potential risk factors for vitamin D deficiency in children were recorded. Patients who were already receiving treatment for vitamin D deficiency were excluded. The collected data were analysed using standard statistical methods.

RESULTS

Of 26,818 patients under 18 years of age who attended the outpatient clinic, 1519 underwent 25-hydroxyvitamin D testing; 51% were male ( 755). After applying the exclusion criteria, 1311 participants were included, 755 (58%) of whom had vitamin D concentrations of ≤50 nmol/L. Vitamin D deficiency was more common in children aged ≥10 years (69%) than in those <10 years of age (53%) ( < 0.0001). The highest prevalence of vitamin D deficiency was in those older than 16 years (86%). More females (63%,  407) than males (52%,  348) were identified as vitamin D-deficient ( 0.0001). Vitamin D deficiency was more commonly identified during summer and autumn (59%) than in winter and spring (44%,  < 0.00001).

CONCLUSION

Vitamin D deficiency is prevalent in children seeking medical care in the UAE, especially in girls, older children and adolescents, and during the summer and autumn. Paediatricians should have a low screening threshold for hypovitaminosis D, or widespread supplementation should be considered.

摘要

背景

尽管阳光充足,但维生素 D 缺乏症在中东仍然很普遍。本研究旨在确定阿布扎比一家三级医院的儿童和青少年维生素 D 缺乏症的发生率,并确定相关的危险因素。

方法

使用阿布扎比谢赫·沙赫布特医学城 2020 年 1 月 1 日至 2021 年 12 月 31 日期间接受 25-羟维生素 D 检测的儿科患者的电子病历进行回顾性观察性研究。记录了年龄、性别、种族、体重、体重指数和儿童维生素 D 缺乏症的其他潜在危险因素的数据。已接受维生素 D 缺乏症治疗的患者被排除在外。使用标准统计方法对收集的数据进行分析。

结果

在 18 岁以下就诊的 26818 名患者中,有 1519 名接受了 25-羟维生素 D 检测;其中 51%为男性(755 名)。应用排除标准后,共纳入 1311 名参与者,其中 755 名(58%)的维生素 D 浓度≤50nmol/L。维生素 D 缺乏症在 10 岁及以上儿童中更为常见(69%),而在 10 岁以下儿童中则较少见(53%)(<0.0001)。年龄大于 16 岁的人群中维生素 D 缺乏症的患病率最高(86%)。与男性(52%,348 名)相比,女性(63%,407 名)更易发生维生素 D 缺乏症(<0.0001)。维生素 D 缺乏症在夏季和秋季(59%)更为常见,而在冬季和春季(44%)则较少见(<0.00001)。

结论

在阿联酋寻求医疗服务的儿童中,维生素 D 缺乏症很常见,尤其是女孩、年龄较大的儿童和青少年,以及夏季和秋季。儿科医生应降低维生素 D 缺乏症的筛查阈值,或考虑广泛补充维生素 D。

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