Department of Hematology, The First Affiliated Hospital of Ningbo University, Ningbo, China.
J Int Med Res. 2024 Sep;52(9):3000605241274581. doi: 10.1177/03000605241274581.
Pneumatosis cystoides intestinalis (PCI) is a rare condition characterized by air accumulation within the subserosa or submucosa of the gastrointestinal wall. We herein report a case involving a woman in her early 30s who developed PCI after undergoing allogeneic hematopoietic stem cell transplantation (HSCT) for acute lymphoblastic leukemia. The patient had a history of multiple COVID-19 infections. Imaging revealed extensive pneumoperitoneum and mesenteric emphysema; nevertheless, the patient remained clinically stable with a benign abdominal examination. She eventually recovered after 1 month of conservative treatment. We believe the PCI in this case had a multifactorial etiology, potentially involving both HSCT and COVID-19. Raising awareness of PCI may help avoid unnecessary surgical interventions and associated morbidity.
肠气囊肿症（PCI）是一种罕见的疾病，其特征是胃肠道壁的浆膜下或黏膜下积聚空气。本文报告了一例 30 多岁的女性病例，该患者在因急性淋巴细胞白血病接受异基因造血干细胞移植（HSCT）后发生 PCI。患者有多次 COVID-19 感染史。影像学检查显示广泛的气腹和肠系膜积气；然而，尽管腹部检查良性，患者仍保持临床稳定。经过 1 个月的保守治疗，她最终康复。我们认为本例 PCI 的病因是多因素的，可能同时涉及 HSCT 和 COVID-19。提高对 PCI 的认识可能有助于避免不必要的手术干预和相关发病率。
