Groninger Ellis, Hulscher Jan B F, Timmer Bert, Tamminga Rienk Y J, Broens Paul M A
Department of Pediatric Oncology/Hematology of the Beatrix Children's Hospital, University of Groningen, The Netherlands.
J Pediatr Hematol Oncol. 2010 Mar;32(2):141-3. doi: 10.1097/MPH.0b013e3181ced397.
Intraperitoneal free air in a child with acute lymphoblastic leukemia (ALL) treated with induction chemotherapy is an ominous sign suspective of gastrointestinal perforation. We report a case of pneumatosis cystoides intestinalis (PCI) with free intraperitoneal air without bowel perforation in a child with Down syndrome during ALL induction treatment. PCI is a physical sign characterized by gas-filled cysts of the submucosa or subserosa of the bowel that can lead to pneumoperitoneum. Clinical management of this case in respect to reported literature on PCI and specific characteristics of patients treated with ALL induction chemotherapy are discussed.
急性淋巴细胞白血病（ALL）患儿在诱导化疗期间出现腹腔内游离气体是提示胃肠道穿孔的不祥征兆。我们报告1例唐氏综合征患儿在ALL诱导治疗期间发生肠壁囊样积气（PCI）且伴有腹腔内游离气体但无肠穿孔的病例。PCI是一种体征，其特征为肠黏膜下层或浆膜下层出现充满气体的囊肿，可导致气腹。结合已发表的关于PCI的文献以及接受ALL诱导化疗患者的具体特征，对该病例的临床处理进行了讨论。
