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国际罕见癌症网络和联盟在神经肿瘤学领域的成就。

Achievements of international rare cancers networks and consortia in the neuro-oncology field.

机构信息

Nervous System Medical Oncology Department, IRCCS Istituto delle Scienze Neurologiche di Bologna, Bologna, Italy.

Sorbonne Université, Inserm, CNRS, UMR S 1127, Institut du Cerveau et de la Moelle Épinière, ICM, AP-HP, Hôpitaux Universitaires La Pitié Salpêtrière - Charles Foix, Service de Neurologie 2-Mazarin, Paris, France.

出版信息

Curr Opin Oncol. 2024 Nov 1;36(6):554-559. doi: 10.1097/CCO.0000000000001097. Epub 2024 Aug 28.

Abstract

PURPOSE OF REVIEW

In this review, we investigated the role of European oncological networks on management and care of patients with central nervous system (CNS) malignancies.

RECENT FINDINGS

Within this universe of tumors, malignancies of the central nervous system (CNS) malignancies represent a challenge because of several reasons such as biological complexity, the need of dedicated experienced physicians (surgeons, pathologists, radiologists and neuro-oncologists) and tertiary healthcare providers. Limits to the development of effective and innovative care are represented by the rarity of these tumors and their extreme heterogeneity in terms of clinical presentation, course of the disease, genetic assessments and site of presentation. The oncological networks are societies or associations, which make possible to connect patients, scientists, doctors and researchers together allowing to obtain several improvements.

SUMMARY

Oncological networks can cooperate to increase accrual rate and speed in clinical trials, share data about CNS malignancy management and improve knowledge toward this class of tumors within patients and health operators promoting equity and high standard of care.

摘要

目的综述

在本次综述中,我们研究了欧洲肿瘤网络在中枢神经系统(CNS)恶性肿瘤患者管理和护理中的作用。

最近的发现

在这个肿瘤领域中,中枢神经系统(CNS)恶性肿瘤的治疗极具挑战性,这是因为多种原因,包括生物学复杂性、对专门的有经验的医生(外科医生、病理学家、放射科医生和神经肿瘤学家)和三级保健提供者的需求。发展有效和创新护理的限制因素是这些肿瘤的罕见性及其在临床表现、疾病过程、遗传评估和发病部位方面的极端异质性。肿瘤网络是将患者、科学家、医生和研究人员联系在一起的协会或团体,使其能够获得多项改进。

总结

肿瘤网络可以合作提高临床试验的入组率和速度,共享 CNS 恶性肿瘤管理方面的数据,并提高患者和卫生工作者对这一类肿瘤的认识,促进公平和高标准的护理。

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