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基于人工智能医学影像分析的左归丸增强早衰大鼠卵巢功能及皮肤弹性修复作用机制。

Mechanism of Zuogui pill enhancing ovarian function and skin elastic repair in premature aging rats based on artificial intelligence medical image analysis.

机构信息

Department of Obstetrics and Gynecology, Putuo Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.

Department of Gynecology of Traditional Chinese Medicine, Putuo Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.

出版信息

Skin Res Technol. 2024 Sep;30(9):e70050. doi: 10.1111/srt.70050.

Abstract

BACKGROUND

AI medical image analysis shows potential applications in research on premature aging and skin. The purpose of this study was to explore the mechanism of the Zuogui pill based on artificial intelligence medical image analysis on ovarian function enhancement and skin elasticity repair in rats with premature aging.

MATERIALS AND METHODS

The premature aging rat model was established by using an experimental animal model. Then Zuogui pills were injected into the rats with premature aging, and the images were detected by an optical microscope. Then, through the analysis of artificial intelligence medical images, the image data is analyzed to evaluate the indicators of ovarian function.

RESULTS

Through optical microscope image detection, we observed that the Zuogui pill played an active role in repairing ovarian tissue structure and increasing the number of follicles in mice, and Zuogui pill also significantly increased the level of progesterone in the blood of mice.

CONCLUSION

Most of the ZGP-induced outcomes are significantly dose-dependent.

摘要

背景

人工智能医学图像分析在研究早衰和皮肤方面显示出潜在的应用。本研究旨在探讨基于人工智能医学图像分析的左归丸对早衰大鼠卵巢功能增强和皮肤弹性修复的作用机制。

材料和方法

采用实验动物模型建立早衰大鼠模型,然后对早衰大鼠进行左归丸注射,并通过光学显微镜进行图像检测,再通过人工智能医学图像分析,对图像数据进行分析,评估卵巢功能指标。

结果

通过光学显微镜图像检测,我们观察到左归丸在修复卵巢组织结构和增加小鼠卵泡数量方面发挥了积极作用,并且左归丸还显著提高了小鼠血液中孕酮的水平。

结论

大多数左归丸诱导的结果与剂量呈显著的相关性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fc5b/11381913/02d379c75c20/SRT-30-e70050-g001.jpg

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