基于基因组的早期检测筛查：胃肠道癌症前瞻性试验及新兴策略的文献综述
Genomic-Based Early Detection Screening: A Literature Review of Prospective Trials and Emerging Strategies for Gastrointestinal Cancers.
作者信息
Tizpa Eemon, Sharzehi Kaveh, Nabavizadeh Nima
机构信息
Radiation Oncology, Washington State University Elson S. Floyd College of Medicine, Spokane, USA.
Gastroenterology and Hepatology, Oregon Health and Science University School of Medicine, Portland, USA.
出版信息
Cureus. 2024 Sep 7;16(9):e68881. doi: 10.7759/cureus.68881. eCollection 2024 Sep.
Abstract
Numerous genomic-based early detection screening tests are being developed. These tests have the potential to revolutionize current single-organ screening paradigms, especially in gastrointestinal cancers. In this review, we underscore the performance of these genomic-based early detection tests based on prospective clinical trials. Moreover, we discuss a professional advancement for gastroenterologists in the diagnostic assessment of individuals who are cancer signal positive.
摘要
许多基于基因组的早期检测筛查测试正在研发中。这些测试有可能彻底改变当前的单器官筛查模式，尤其是在胃肠道癌症方面。在本综述中，我们根据前瞻性临床试验强调了这些基于基因组的早期检测测试的性能。此外，我们还讨论了胃肠病学家在对癌症信号呈阳性的个体进行诊断评估方面的专业进展。
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