Improvement of NaCas/DGMO complex emulsion on resveratrol stability, bioaccessibility, bioavailability and gut microbiota.

Evaluation for biological impact of food emulsions is fundamental for their application. In present study, we utilized a NaCas-DGMO (sodium caseinate-decylglycerol monooleate) stabilized emulsion to improve resveratrol's (Res) stability, and bioavailability. The interaction between complex emulsion and gut microbiota was further explored. Results indicated NaCas-DGMO emulsion achieved a loading rate of 92 % for Res and significantly enhanced storage and photo stability of Res. gastrointestinal digestion highlighted a significant improvement in Res's bioaccessibility. pharmacokinetic tests showed a notable 3.1-fold increase in oral bioavailability, with a prolonged T of 6 h post-administration. Gut microbiota analysis revealed that the emulsion promoted beneficial bacteria, like , which produce short-chain fatty acids. Consequently, the findings proved potential of NaCas-DGMO stabled emulsion as carriers for bioactive substances in the food industry. The innovative methodology employed in assessing biological effects provides valuable insights for future research in related field.