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马伤口皮肤移植的综述:适应症与技术

Review of skin grafting in equine wounds: indications and techniques.

作者信息

Williams Zoë J, Pezzanite Lynn M, Hendrickson Dean A

机构信息

Department of Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, 300 West Drake Road, Fort Collins, Colorado 80523, USA.

出版信息

Equine Vet Educ. 2024 Sep;36(9):484-493. doi: 10.1111/eve.13964. Epub 2024 Feb 28.

DOI:10.1111/eve.13964
PMID:39246829
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11376462/
Abstract

Skin grafting is a simple technique that can be performed by equine practitioners to improve cosmetic outcomes in wounds with large skin defects that would not heal functionally or cosmetically with standard wound therapy interventions. Successful skin grafting is not difficult but relies upon appropriate preparation of the wound bed and effective immobilisation of the grafted area after skin graft placement. Prior to grafting, the wound bed should be treated with a moist wound healing dressing to prepare the granulation tissue bed to receive the graft. For best results, skin grafts should be placed in wounds free of infection with healthy granulation tissue, and motion should be reduced in the graft region in the early postoperative period. When successful, skin grafts cover granulation tissue and encourage wound contraction and epithelialisation while decreasing exuberant granulation tissue resulting in a more cosmetic result. This review will advance practitioners' understanding of skin grafting in horses, including graft classification and techniques, donor site selection, recipient site preparation, postoperative management strategies to optimise graft retention and ongoing research in this field.

摘要

皮肤移植是一种简单的技术,马医可以实施该技术,以改善大面积皮肤缺损伤口的美容效果,这些伤口采用标准伤口治疗干预措施无法实现功能或美容愈合。成功的皮肤移植并不困难,但依赖于对伤口床的适当准备以及皮肤移植后对移植区域的有效固定。在移植前,伤口床应使用湿性伤口愈合敷料进行处理,以准备肉芽组织床来接受移植。为获得最佳效果,皮肤移植应放置在无感染且有健康肉芽组织的伤口中,术后早期应减少移植区域的活动。成功时,皮肤移植覆盖肉芽组织,促进伤口收缩和上皮化,同时减少过度增生的肉芽组织,从而获得更美观的效果。本综述将增进从业者对马皮肤移植的理解,包括移植分类和技术、供体部位选择、受体部位准备、优化移植保留的术后管理策略以及该领域的 ongoing research。 (注:“ongoing research”直译为“正在进行的研究”,这里保留英文未翻译,因为不清楚具体所指内容,若有上下文可进一步准确翻译)

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本文引用的文献

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Negative-Pressure Wound Therapy (NPWT) in Horses: A Scoping Review.马匹负压伤口治疗(NPWT):一项范围综述。
Vet Sci. 2023 Aug 6;10(8):507. doi: 10.3390/vetsci10080507.
2
Split-Thickness and Full-Thickness Skin Grafts.中厚皮片和全厚皮片
Plast Aesthet Nurs (Phila). 2022;42(3):122-123. doi: 10.1097/PSN.0000000000000453.
3
Application of an instructive hydrogel accelerates re-epithelialization of xenografted human skin wounds.一种有指导作用的水凝胶加速异种移植人皮伤口的再上皮化。
Sci Rep. 2022 Aug 20;12(1):14233. doi: 10.1038/s41598-022-18204-w.
4
Healing time of experimentally induced distal limb wounds in horses is not reduced by local injection of equine-origin liquid amnion allograft.局部注射马源液体羊膜同种异体移植物不会减少实验诱导的马肢远端伤口的愈合时间。
Am J Vet Res. 2022 Jul 13;83(8):ajvr.21.10.0169. doi: 10.2460/ajvr.21.10.0169.
5
Free Skin Grafting to Reconstruct Donor Sites after Radial Forearm Flap Harvesting: A Prospective Study with Platelet-Rich Fibrin (PRF).桡侧前臂皮瓣切取后采用富血小板纤维蛋白(PRF)行游离皮片移植修复供区:一项前瞻性研究
J Clin Med. 2022 Jun 17;11(12):3506. doi: 10.3390/jcm11123506.
6
Comparative study between skin micrografting (Meek technique) and meshed skin grafts in paediatric burns.皮肤微粒移植(Meek 技术)与网状皮片移植在小儿烧伤中的对比研究。
Burns. 2022 Nov;48(7):1632-1644. doi: 10.1016/j.burns.2022.01.016. Epub 2022 Jan 29.
7
Acellular fish skin grafts for the management of wounds in dogs and cats: 17 cases (2019-2021).应用脱细胞鱼皮移植物治疗犬猫创伤:17 例病例报告(2019-2021 年)。
Am J Vet Res. 2021 Nov 25;83(2):188-192. doi: 10.2460/ajvr.21.09.0140.
8
Use of Negative Pressure Wound Therapy in the Treatment of Limb Wounds: A Case Series of 42 Horses.负压伤口疗法在四肢伤口治疗中的应用:42 例马的病例系列。
J Equine Vet Sci. 2021 Nov;106:103725. doi: 10.1016/j.jevs.2021.103725. Epub 2021 Jul 31.
9
Biomechanics of Wound Healing in an Equine Limb Model: Effect of Location and Treatment with a Peptide-Modified Collagen-Chitosan Hydrogel.马肢体模型中伤口愈合的生物力学:肽修饰的胶原-壳聚糖水凝胶的位置和治疗效果
ACS Biomater Sci Eng. 2021 Jan 11;7(1):265-278. doi: 10.1021/acsbiomaterials.0c01431. Epub 2020 Dec 20.
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Evaluation of fish skin as a biological dressing for metacarpal wounds in donkeys.评估鱼皮作为驴掌骨伤口生物敷料的效果。
BMC Vet Res. 2020 Dec 3;16(1):472. doi: 10.1186/s12917-020-02693-w.