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使用隐匿性肾脏疾病筛查(SCORED)问卷对无症状患者进行糖尿病肾病筛查:一项横断面研究。

Use of the Screening for Occult Renal Disease (SCORED) Questionnaire to Screen Diabetic Nephropathy in Asymptomatic Patients: A Cross-Sectional Study.

作者信息

Aleixo Flávio Augusto P, Assunção Luíza Israel S, Rodrigues Matheus Lucca Ângelo C, Vieira Laura Lisboa O, Vilela Vitor Hugo M, Correa Cristiane R

机构信息

Surgery, Faculdade de Ciências Médicas de Minas Gerais, Belo Horizonte, BRA.

Internal Medicine, Faculdade de Ciências Médicas de Minas Gerais, Belo Horizonte, BRA.

出版信息

Cureus. 2024 Aug 6;16(8):e66327. doi: 10.7759/cureus.66327. eCollection 2024 Aug.

DOI:10.7759/cureus.66327
PMID:39246949
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11379342/
Abstract

INTRODUCTION

The 2007 Screening for Occult Renal Disease (SCORED) questionnaire accesses risk factors for chronic kidney disease (CKD) and makes it possible to screen high-risk patients, being adapted and validated for the Brazilian culture in 2012. The present study evaluated the questionnaire's ability to predict the occurrence of CKD in asymptomatic patients, as well as identify a high risk for developing the disease.

METHODS

This was an analytical observational study with a cross-sectional design carried out in two stages: answering the SCORED and performing fasting blood glucose and creatinine tests. The participants were patients at the Hospital das Clínicas of the Federal University of Minas Gerais (HC-UFMG) with scheduled creatinine and fasting blood glucose tests, respecting the inclusion and exclusion criteria defined for the study. SCORED was applied with questions covering gender, age, proteinuria, and diabetes, being classified as high or low risk for CKD. The data collected were height, weight, age, sex, diagnosis of diabetes mellitus, and fasting blood glucose.

RESULTS

The sample space was 212 individuals, the majority of whom were female (N=130, 61.3%), with a median of 58 years of age. The prevalence of CKD was 15.6% (N=33) with a sensitivity of 90.9%, a specificity of 30.2%, a positive predictive value of 19.4%, a negative predictive value of 94.7%, and a diagnostic accuracy of 39.7%.

CONCLUSION

We concluded that the SCORED questionnaire can be a useful tool for screening CKD in asymptomatic patients and also that there is a relationship was detected between glycemic changes and an increased risk for CKD.

摘要

引言

2007年隐匿性肾病筛查(SCORED)问卷可评估慢性肾脏病(CKD)的危险因素,并能够筛查高危患者,该问卷于2012年针对巴西文化进行了改编和验证。本研究评估了该问卷预测无症状患者CKD发生的能力,以及识别疾病发生的高风险。

方法

这是一项采用横断面设计的分析性观察研究,分两个阶段进行:回答SCORED问卷并进行空腹血糖和肌酐检测。参与者为米纳斯吉拉斯联邦大学临床医院(HC-UFMG)计划进行肌酐和空腹血糖检测的患者,符合该研究定义的纳入和排除标准。应用SCORED问卷,问题涵盖性别、年龄、蛋白尿和糖尿病,分为CKD高风险或低风险。收集的数据包括身高、体重、年龄、性别、糖尿病诊断和空腹血糖。

结果

样本量为212人,其中大多数为女性(N = 130,61.3%),年龄中位数为58岁。CKD的患病率为15.6%(N = 33),敏感性为90.9%,特异性为30.2%,阳性预测值为19.4%,阴性预测值为94.7%,诊断准确性为39.7%。

结论

我们得出结论,SCORED问卷可作为筛查无症状患者CKD的有用工具,并且还检测到血糖变化与CKD风险增加之间存在关联。

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Translation, cultural adaptation, and validation of the screening for occult renal disease (SCORED) questionnaire to Brazilian Portuguese.将隐匿性肾病筛查问卷(SCORED)翻译成巴西葡萄牙语、进行文化调适及验证。
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Chronic kidney disease: importance of early diagnosis, immediate referral and structured interdisciplinary approach to improve outcomes in patients not yet on dialysis.慢性肾脏病:早期诊断、及时转诊及采用结构化多学科方法对尚未接受透析治疗的患者改善预后的重要性。
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