Priya Madhu, Dubey Surekha A, Gorripati Jahnavi P
Department of Prosthodontics, Sharad Pawar Dental College and Hospital, Datta Meghe Institute of Higher Education and Research, Wardha, IND.
Cureus. 2024 Aug 7;16(8):e66406. doi: 10.7759/cureus.66406. eCollection 2024 Aug.
Parkinson's disease (PD) affects one to two out of every 1,000 individuals. PD, being age-related, is affecting a percentage of those over and around the sixth decade. Lewy bodies containing α-synuclein and a reduction in dopaminergic neurons in the substantia nigra, which impairs the region's capacity to promote voluntary movements, are the main neuropathological findings. The three main symptoms of PD are stiffness, bradykinesia, and tremor. Treatment of edentulous conditions in patients with PD becomes a challenge due to decreased neuromuscular coordination and decreased mobility. This case report outlines a 64-year-old male patient with complete edentulism suffering from PD. Complete denture fabrication was done using the concepts of the neutral zone and denture characterization. Significantly, it not only improves the stability of the dentures but also establishes good denture aesthetics.
帕金森病（PD）每1000人中就有1至2人受影响。PD与年龄相关，影响着六旬及六旬左右人群中的一定比例。主要的神经病理学发现是含有α-突触核蛋白的路易小体以及黑质中多巴胺能神经元减少，这损害了该区域促进自主运动的能力。PD的三大主要症状是僵硬、运动迟缓及震颤。由于神经肌肉协调性下降和活动能力降低，PD患者无牙状况的治疗成为一项挑战。本病例报告概述了一名患有PD的64岁男性全口无牙患者。使用中性区和义齿个性化概念完成了全口义齿制作。值得注意的是，这不仅提高了义齿的稳定性，还建立了良好的义齿美观效果。
