Almadhoun Mohammed Khaleel I Kh, Morcos Rami Kamal Atiya, Alsadoun Lara, Bokhari Syed Faqeer Hussain, Ahmed Zeeshan, Khilji Faria, Hasan Abdul Haseeb, Bakht Danyal, Abuelgasim Omer, Altayb Ismail Mohamedalamin Alnoor
Medicine and Surgery, Mutah University, Karak, JOR.
General Surgery, Ministry of Health Holdings, Riyadh, SAU.
Cureus. 2024 Aug 8;16(8):e66444. doi: 10.7759/cureus.66444. eCollection 2024 Aug.
Hirschsprung disease (HD) is a congenital disorder characterized by the absence of ganglion cells in the distal colon and rectum, leading to functional obstruction and severe constipation. Over the past decades, the surgical management of HD has significantly evolved, with minimally invasive surgery (MIS) techniques revolutionizing treatment approaches. This review explores recent innovations in MIS for HD, focusing on laparoscopic, transanal endorectal pull-through (TERPT), and robotic-assisted techniques. These approaches offer numerous advantages over traditional open procedures, including reduced surgical trauma, improved cosmesis, faster recovery times, and potentially lower complication rates. Laparoscopic surgery has become widely adopted, providing excellent visualization and precise dissection. TERPT has gained popularity for short-segment disease, offering a completely transanal approach with minimal scarring. Robotic-assisted surgery represents the cutting edge, enhancing surgical precision and dexterity. The review also examines emerging technologies and future directions, such as advanced imaging techniques, artificial intelligence applications, and potential developments in tissue engineering. While MIS techniques have shown promising outcomes, challenges remain in standardizing approaches, addressing long-segment disease, and optimizing long-term functional results. The future of HD surgery lies in personalized approaches that integrate genetic and molecular profiling with advanced surgical technologies. As the field continues to evolve, comprehensive long-term studies and efforts to improve access to specialized care will be crucial to further enhancing outcomes for patients with HD.
先天性巨结肠(HD)是一种先天性疾病,其特征是远端结肠和直肠中缺乏神经节细胞,导致功能性梗阻和严重便秘。在过去几十年中,HD的外科治疗有了显著进展,微创手术(MIS)技术彻底改变了治疗方法。本综述探讨了HD的MIS最新创新,重点关注腹腔镜手术、经肛门直肠拖出术(TERPT)和机器人辅助技术。这些方法相对于传统开放手术具有众多优势,包括减少手术创伤、改善美观效果、缩短恢复时间以及可能降低并发症发生率。腹腔镜手术已被广泛采用,提供了良好的视野和精确的解剖。TERPT因适用于短段病变而受到欢迎,提供了一种完全经肛门的方法,疤痕最小。机器人辅助手术代表了前沿技术,提高了手术精度和灵活性。该综述还研究了新兴技术和未来方向,如先进的成像技术、人工智能应用以及组织工程的潜在发展。虽然MIS技术已显示出有前景的结果,但在标准化方法、处理长段病变以及优化长期功能结果方面仍存在挑战。HD手术的未来在于将基因和分子分析与先进手术技术相结合的个性化方法。随着该领域的不断发展,全面的长期研究以及改善获得专科护理的努力对于进一步提高HD患者的治疗效果至关重要。