Ladriñán-Maestro Arturo, Sánchez-Infante Jorge, Martín-Vera Daniel, Sánchez-Sierra Alberto
School for Doctoral Studies and Research, Universidad Europea de Madrid, Madrid, Spain.
Research Group on Exercise Therapy and Functional Rehabilitation, Faculty of Sports Sciences, Universidad Europea de Madrid, Madrid, Spain.
Front Physiol. 2024 Aug 23;15:1457019. doi: 10.3389/fphys.2024.1457019. eCollection 2024.
Inspiratory muscle fatigue has been shown to have effects on the autonomic nervous system and physical condition. This study aimed to evaluate the influence of an inspiratory muscle fatigue protocol on respiratory muscle strength and heart rate variability in healthy youths. A randomized controlled clinical trial, employing double-blinding, was conducted with twenty-seven participants aged 18-45 years, non-smokers and engaged in sports activity at least three times a week for a minimum of 1 year. Participants were randomly assigned to three groups: Inspiratory Muscle Fatigue group, Activation group, and Control group. Measurements of heart rate variability, diaphragmatic ultrasound, and maximum inspiratory pressure were taken at two stages: before the intervention and immediately after treatment. In our results with respect to baseline to post-treatment, the inspiratory muscle fatigue group showed lower values in the Sniff contraction velocity variable (10.96 cm/s ± 1.99-8.34 cm/s ± 1.23; < 0.01) and higher values in the activation group (10.59 cm/s ± 0.89-12.66 cm/s ± 1.15; < 0.01) with respect to the control group (10.27 cm/s ± 1.48-9.97 cm/s ± 1.42). On the other hand, the inspiratory muscle fatigue group showed higher values in the Low frequency variable (49.37 n.u. ± 13.91 to 69.48 n.u. ± 8.22; < 0.01) and lower values in the activation group (57.92 n.u. ± 8.37 to 41.59 n.u. ± 11.21; < 0.01) with respect to the control group (50.83 n.u. ± 17.30 to 52.10 n.u. ± 20.64). Additionally, significant correlations were found between respiratory variables and heart rate variability variables. Acute fatigue of the inspiratory musculature appears to negatively impact heart rate variability and inspiratory muscle strength in healthy youths. https://clinicaltrials.gov/study/NCT06278714; Identifier: NCT06278714.
吸气肌疲劳已被证明会对自主神经系统和身体状况产生影响。本研究旨在评估吸气肌疲劳方案对健康青年呼吸肌力量和心率变异性的影响。对27名年龄在18 - 45岁、不吸烟且每周至少进行三次体育活动至少一年的参与者进行了一项采用双盲法的随机对照临床试验。参与者被随机分为三组：吸气肌疲劳组、激活组和对照组。在两个阶段进行心率变异性、膈肌超声和最大吸气压力的测量：干预前和治疗后立即测量。在我们关于基线至治疗后的结果中，吸气肌疲劳组在嗅吸收缩速度变量方面显示出较低的值（10.96厘米/秒±1.99 - 8.34厘米/秒±1.23；<0.01），激活组相对于对照组（10.27厘米/秒±1.48 - 9.97厘米/秒±1.42）显示出较高的值（10.59厘米/秒±0.89 - 12.66厘米/秒±1.15；<0.01）。另一方面，吸气肌疲劳组在低频变量方面显示出较高的值（49.37标准化单位±13.91至69.48标准化单位±8.22；<0.01），激活组相对于对照组（50.83标准化单位±17.30至52.10标准化单位±20.64）显示出较低的值（57.92标准化单位±8.37至41.59标准化单位±11.21；<0.01）。此外，在呼吸变量和心率变异性变量之间发现了显著的相关性。吸气肌肉组织的急性疲劳似乎对健康青年的心率变异性和吸气肌力量产生负面影响。https://clinicaltrials.gov/study/NCT06278714；标识符：NCT06278714。
