来自枯草芽孢杆菌噬菌体phi 3T的胸苷酸合成酶基因（thyP3）的核苷酸序列。
Nucleotide sequence of the thymidylate synthetase gene (thyP3) from the Bacillus subtilis phage phi 3T.
作者信息
Kenny E, Atkinson T, Hartley B S
出版信息
Gene. 1985;34(2-3):335-42. doi: 10.1016/0378-1119(85)90142-8.
PMID:3924741
Abstract
The thyP3 gene, encoding thymidylate synthetase, from the Bacillus subtilis phage phi 3T has been cloned and the nucleotide sequence determined. The derived amino acid sequence indicates a subunit Mr of 32 748. The primary amino acid sequence is compared with the sequences of the analogous proteins specified by Escherichia coli (thyA), Lactobacillus casei, (thyA) and phage T4 (td). Extensive conservation exists in all four sequences implying a shared tertiary structure.
摘要
已克隆出枯草芽孢杆菌噬菌体phi 3T中编码胸苷酸合成酶的thyP3基因，并测定了其核苷酸序列。推导的氨基酸序列表明亚基的分子量为32748。将其一级氨基酸序列与大肠杆菌（thyA）、干酪乳杆菌（thyA）和噬菌体T4（td）所指定的类似蛋白质的序列进行了比较。所有这四个序列中都存在广泛的保守性，这意味着它们具有共同的三级结构。
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