Yoshida Takao, Watanabe Yoshiki, Hiratsuka Yasuyuki
Department of Otolaryngology, Head and Neck Surgery, Japanese Red Cross Osaka Hospital, Osaka, Japan.
Radiol Case Rep. 2024 Aug 16;19(11):4917-4920. doi: 10.1016/j.radcr.2024.07.140. eCollection 2024 Nov.
Lymphoepithelial carcinoma of the submandibular gland is an extremely rare condition; therefore, no clear clinical features or established treatment is available for this. A 58-year-old Japanese man who came to our hospital with the complaint of swelling of the left submandibular region was diagnosed with stage IVa, T4aN2bM0 lymphoepithelial carcinoma of the submandibular gland. We also examined the relationship between the tumor and Epstein-Barr virus by Epstein-Barr virus encoded ribonucleoprotein in situ hybridization. The patient was treated by performing segmental mandibulectomy, neck dissection, mandibular reconstruction, and adjuvant chemoradiotherapy. After 2 years of treatment, good progress has been observed in the patient without any signs of recurrence. Here, we have reported the treatment of a patient with lymphoepithelial carcinoma of the submandibular gland using literature review.
下颌下腺淋巴上皮癌是一种极为罕见的疾病；因此，对于此病尚无明确的临床特征或既定的治疗方法。一名58岁的日本男性因左侧下颌下区肿胀前来我院就诊，被诊断为IVa期、T4aN2bM0下颌下腺淋巴上皮癌。我们还通过爱泼斯坦-巴尔病毒编码核糖核蛋白原位杂交检测了肿瘤与爱泼斯坦-巴尔病毒之间的关系。该患者接受了下颌骨节段性切除术、颈部清扫术、下颌骨重建术及辅助放化疗。治疗2年后，患者病情进展良好，无任何复发迹象。在此，我们通过文献回顾报道了一例下颌下腺淋巴上皮癌患者的治疗情况。
