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采用含5-氟尿嘧啶的方案治疗聚己内酯类真皮填充剂所致的面动脉栓塞

Treatment of Facial Artery Embolization Caused by Polycaprolactone-based Dermal Filler with a Regimen Including 5-Fluorouracil.

作者信息

Guo Fengfeng, Xia Yuxi, Wei Qingqian, Zhuang Jun, Li Jinge, Hu Jintian

机构信息

From the Department of Cosmetic Injection Center, Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, PR China.

School of Basic Medicine, Xinxiang Medical University, Xinxiang, Henan, PR China.

出版信息

Plast Reconstr Surg Glob Open. 2024 Sep 6;12(9):e6140. doi: 10.1097/GOX.0000000000006140. eCollection 2024 Sep.

DOI:10.1097/GOX.0000000000006140
PMID:39247572
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11379482/
Abstract

Polycaprolactone-based fillers are commonly used in plastic surgery to improve facial aging. However, adverse vascular events following these injections have been reported. An arterial embolism is a rare but serious complication associated with injectable filler procedures. We report a case of arterial embolism in a 35-year-old woman who received a polycaprolactone-based dermal filler at the nasal base and was treated with a regimen containing 5-fluorouracil. We discuss the potential causes of the patient's condition and assess the superiority of our method over conventional approaches. Before treatment, ultrasound detected a decreased flow velocity in the patient's right medial canthus artery with distal hypoperfusion, which improved significantly posttreatment. Long-term follow-up revealed near-disappearance of facial scarring. Our treatment effectively addressed facial artery embolism without any reported adverse reactions.

摘要

聚己内酯基填充剂常用于整形手术以改善面部老化。然而,已有这些注射后发生不良血管事件的报道。动脉栓塞是与可注射填充剂手术相关的一种罕见但严重的并发症。我们报告一例35岁女性的动脉栓塞病例,该患者在鼻基底接受了聚己内酯基真皮填充剂,并接受了含5-氟尿嘧啶的治疗方案。我们讨论了患者病情的潜在原因,并评估了我们的方法相对于传统方法的优越性。治疗前,超声检测到患者右内眦动脉血流速度降低且远端灌注不足,治疗后明显改善。长期随访显示面部瘢痕几乎消失。我们的治疗有效解决了面动脉栓塞问题,且未报告任何不良反应。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/24be/11379482/7d5484573fac/gox-12-e6140-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/24be/11379482/7d5484573fac/gox-12-e6140-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/24be/11379482/7d5484573fac/gox-12-e6140-g001.jpg

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