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甲状旁腺切除术恢复了伴有肾性骨营养不良的被忽视的股骨颈骨折患者的骨密度:一例报告。

Parathyroidectomy restored bone mineral density in a neglected femoral neck fracture with renal osteodystrophy: A case report.

作者信息

Lin Tzu-Ching, Lin Shih-Wei, Yeh Kuang-Ting

机构信息

Department of Education, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien 970473, Taiwan Province, China.

Department of Orthopedics, Ten-Chan Medical Group, Taoyuan 320003, Taiwan Province, China.

出版信息

World J Clin Cases. 2024 Sep 6;12(25):5761-5768. doi: 10.12998/wjcc.v12.i25.5761.

Abstract

BACKGROUND

This case report contributes to the medical literature by highlighting the successful management of a neglected femoral neck fracture in a patient with renal osteodystrophy and secondary hyperparathyroidism (SHPTH) who was on dialysis due to end-stage renal disease (ESRD). It underscores the efficacy of parathyroidectomy (PTX) in restoring bone mineral density (BMD) and promoting fracture healing, addressing a significant complication in ESRD patients.

CASE SUMMARY

A 36-year-old female with renal osteodystrophy and on dialysis due to ESRD presented with a history of left patellar tendon rupture and later, a right achilles tendon avulsion fracture. Persistent right hip pain led to the discovery of a neglected right femoral neck fracture, which was initially overlooked due to the patient's complex medical history. Two months post-achilles tendon repair, the patient underwent PTX to manage the refractory SHPTH. The postoperative course included rehabilitation and weight-bearing exercises. Remarkably, 2 years after osteosynthesis, radiographic assessments indicated a solid union of the periprothesis fracture and significant improvement in BMD, showcasing the efficacy of the treatment approach.

CONCLUSION

PTX, combined with appropriate rehabilitation, is crucial for improving BMD and fracture healing in ESRD patients with SHPTH.

摘要

背景

本病例报告通过突出对一名因终末期肾病(ESRD)接受透析治疗的肾性骨营养不良和继发性甲状旁腺功能亢进(SHPTH)患者中被忽视的股骨颈骨折的成功处理,为医学文献做出了贡献。它强调了甲状旁腺切除术(PTX)在恢复骨矿物质密度(BMD)和促进骨折愈合方面的有效性,解决了ESRD患者中的一个重大并发症。

病例摘要

一名36岁患有肾性骨营养不良且因ESRD接受透析治疗的女性,有左髌腱断裂病史,后来又出现右跟腱撕脱骨折。持续的右髋部疼痛导致发现一处被忽视的右股骨颈骨折,由于患者复杂的病史,该骨折最初被忽视。跟腱修复术后两个月,患者接受了PTX以治疗难治性SHPTH。术后过程包括康复和负重锻炼。值得注意的是,骨合成术后2年,影像学评估显示假体周围骨折牢固愈合且BMD有显著改善,展示了该治疗方法的有效性。

结论

PTX联合适当的康复治疗对于改善患有SHPTH的ESRD患者的BMD和骨折愈合至关重要。

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