Department of Health Outcomes & Biomedical Informatics, University of Florida, Gainesville, Florida, USA.
Department of Biomedical Informatics, College of Medicine, The Ohio State University, Columbus, Ohio, USA.
Cancer Med. 2024 Sep;13(17):e7079. doi: 10.1002/cam4.7079.
Cancer survivors are at greater risk for cardiovascular-related mortality. Mobile health (mHealth) is an increasingly prevalent strategy for health promotion, but whether it consistently improves cardiorespiratory outcomes after a cancer diagnosis is unknown. We sought to determine the effectiveness of mHealth fitness/physical activity interventions on cardiorespiratory fitness outcomes among cancer patients and survivors.
Leveraging MEDLINE/PubMed, Scopus, and ClinicalTrials.gov, we identified studies through May 2023. Included studies provided a quantitative evaluation of an mHealth intervention in a primary or secondary capacity on cardiorespiratory fitness (6-minute walk test, VOmax, 3-minute step test, or systolic blood pressure; or any mention of cardiac measure) and were meta-analyzed (using a random effects model) if they were a randomized controlled trial with sufficient quantitative information. Four coders were involved in applying inclusion/exclusion criteria, coding using a standardized data extraction sheet, and assessing study quality, with each study coded by at least two.
Of 656 articles, nine (n = 392) met systematic review inclusion criteria (mean age range 19-62 years, 71.9% female, 60.9% breast cancer). Interventions included mobile apps (k = 6), smartwatches (k = 2), or a smartwatch plus a supplemental web/mobile/tablet app (k = 1); median duration of mHealth-use was 12 weeks. Seven (n = 341) fit criteria for meta-analysis. mHealth was associated with improved cardiorespiratory fitness (d = 0.33; 95% CI = 0.07-0.60) compared to a control group. Relationships remained after accounting for lipid-based outcomes (d = 0.30; 95% CI = 0.03-0.56). There was no evidence for heterogeneity or publication-bias.
mHealth exercise interventions appear to be a viable strategy for improving cardiorespiratory fitness after a cancer diagnosis.
癌症幸存者患心血管相关死亡的风险更高。移动健康（mHealth）是一种越来越流行的健康促进策略，但它是否能持续改善癌症诊断后的心肺功能结果尚不清楚。我们旨在确定 mHealth 健身/体育活动干预措施对癌症患者和幸存者心肺功能的有效性。
利用 MEDLINE/PubMed、Scopus 和 ClinicalTrials.gov，我们在 2023 年 5 月之前确定了研究。纳入的研究以原发性或次要容量定量评估了 mHealth 干预措施对心肺功能（6 分钟步行测试、VOmax、3 分钟踏步测试或收缩压；或任何提到心脏措施），并且如果它们是随机对照试验且具有足够的定量信息，则进行了荟萃分析（使用随机效应模型）。四名编码员参与了应用纳入/排除标准、使用标准化数据提取表进行编码以及评估研究质量的工作，每个研究至少由两名编码员进行编码。
在 656 篇文章中，有 9 篇（n=392）符合系统评价纳入标准（平均年龄范围为 19-62 岁，女性占 71.9%，乳腺癌占 60.9%）。干预措施包括移动应用程序（k=6）、智能手表（k=2）或智能手表加补充网络/移动/平板电脑应用程序（k=1）；mHealth 使用的中位数持续时间为 12 周。有 7 篇（n=341）符合荟萃分析标准。与对照组相比，mHealth 与心肺功能改善相关（d=0.33；95%CI=0.07-0.60）。在考虑基于脂质的结果后，关系仍然存在（d=0.30；95%CI=0.03-0.56）。没有异质性或发表偏倚的证据。
mHealth 运动干预措施似乎是癌症诊断后改善心肺功能的可行策略。
