Department of Laboratory Medicine/Clinical Laboratory Medicine Research Center, West China Hospital, Sichuan University, Chengdu 610041, Sichuan, China.
Sichuan Clinical Research Center for Laboratory Medicine, Chengdu 610041, Sichuan, China.
J Mater Chem B. 2024 Sep 18;12(36):8897-8901. doi: 10.1039/d4tb01721h.
The exploration of noble metal-free nanoarrays as high-activity catalytic electrodes for glucose biosensing holds great significance. Herein, we propose a Ni nanoparticle-decorated TiO nanoribbon array on a titanium plate (Ni@TiO/TP) as an effective non-enzymatic glucose biosensing electrode. The as-prepared Ni@TiO/TP electrode demonstrates rapid glucose response, a wide linear response range (1 μM to 1 mM), a low detection limit (0.08 μM, S/N = 3), and high sensitivity (10 060 and 3940 μA mM cm), with good mechanical flexibility and stability. Moreover, it proves efficient in glucose biosensing in real human blood serum and cell culture fluid. Thus, it is highly promising for practical applications.
作为一种高效的非酶葡萄糖生物传感电极，探索无贵金属纳米阵列作为高活性催化电极具有重要意义。在此，我们提出了一种在钛板上修饰有 Ni 纳米颗粒的 TiO 纳米带阵列（Ni@TiO/TP）。所制备的 Ni@TiO/TP 电极具有快速的葡萄糖响应、较宽的线性响应范围（1 μM 至 1 mM）、较低的检测限（0.08 μM，S/N = 3）和较高的灵敏度（10060 和 3940 μA mM cm），具有良好的机械柔韧性和稳定性。此外，它在实际的人血清和细胞培养液中的葡萄糖生物传感中表现出高效性。因此，它在实际应用中具有很高的应用前景。
