A child with systemic onset juvenile idiopathic arthritis and nephrotic syndrome.

INTRODUCTION

Amyloidosis of the kidney is a rare complication in children with juvenile idiopathic arthritis (JIA), more commonly seen with systemic onset juvenile idiopathic arthritis (SOJIA). It usually presents with asymptomatic proteinuria.

CASE REPORT

An 11.5-year-old boy with onset of SOJIA at 6 years of age came to our clinic with anasarca. Urinalysis and serum albumin suggested a diagnosis of nephrotic syndrome (NS) and kidney biopsy confirmed amyloidosis deposits. Treatment with injection tocilizumab was initiated. The proteinuria has decreased, and kidney functions are normal.

CONCLUSION

Children with SOJIA should be monitored for proteinuria so that they can be offered timely appropriate therapy.