Papathanasiou Athanasios, Hindmarsh Dorian, Searle Belinda
Bourn Hall Clinic, High Street, Bourn, CB23 2TN, Cambridge, UK.
Proeon Systems Ltd., Norwich, UK.
J Assist Reprod Genet. 2024 Dec;41(12):3251-3259. doi: 10.1007/s10815-024-03249-9. Epub 2024 Sep 9.
The increasing number of women with underlying health conditions seeking in vitro fertilization (IVF) necessitates a comprehensive risk assessment framework tailored to their needs. This review aims to provide a practical framework for IVF specialists to systematically assess and manage the risks associated with medically complex patients. The GRASP mnemonic (Genetics, Retrieval, Anaesthetics, Stimulation, Pregnancy) is introduced to facilitate a thorough risk assessment process. The review emphasizes the importance of obtaining detailed medical histories, corroborating information from other healthcare providers, and involving maternal medicine specialists in pre-pregnancy counselling. Furthermore, it highlights the ethical considerations of informed consent, advocating for fertility specialists to take a central role in coordinating care and ensuring patient understanding of risks. Continuous health evaluation throughout the IVF process and clear communication of risks are crucial for improving patient outcomes.
越来越多有基础健康问题的女性寻求体外受精（IVF），这就需要一个根据她们的需求量身定制的全面风险评估框架。本综述旨在为IVF专家提供一个实用框架，以便系统地评估和管理与患有复杂疾病的患者相关的风险。引入GRASP助记法（遗传学、取卵、麻醉、刺激、妊娠）以促进全面的风险评估过程。该综述强调获取详细病史、核实其他医疗服务提供者提供的信息以及让母胎医学专家参与孕前咨询的重要性。此外，它突出了知情同意的伦理考量，主张生育专家在协调护理以及确保患者理解风险方面发挥核心作用。在整个IVF过程中持续进行健康评估以及清晰地传达风险对于改善患者预后至关重要。
