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[眼眶神经节细胞瘤]

[Ganglioneuroblastoma of the orbit].

作者信息

Dhermy P, Sekkat A, Moussaoui M, Bellakhdar N, Haye C, Charlot J C

出版信息

J Fr Ophtalmol. 1985;8(2):139-46.

PMID:3924990
Abstract

Ganglioneuroblastoma a transitional tumor of sympathetic origin has not yet been described as involving orbit. It is characterized by a mixture of cells ranging from primitive neuroblast to well differentiated ganglion cells within a neurofibromatous tissue. The prognosis is uncertain, as the tumor may either undergo maturation into a ganglioneuroma or may metastasize widely and rapidly as in neuroblastoma. We may postulate a relationship between ganglioneuroblastoma and Recklinghausen's neurofibromatosis in view of the development of the tumor in conjunction with the phacomatosis.

摘要

神经节神经母细胞瘤是一种起源于交感神经的过渡性肿瘤,此前尚无累及眼眶的相关描述。其特征是在神经纤维瘤组织内存在从原始神经母细胞到分化良好的神经节细胞等多种细胞的混合。预后尚不确定,因为肿瘤可能成熟为神经节神经瘤,也可能像神经母细胞瘤那样广泛且迅速地转移。鉴于该肿瘤与斑痣性错构瘤病同时发生,我们可以推测神经节神经母细胞瘤与冯雷克林霍增氏神经纤维瘤病之间存在关联。

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