Department of Ecology and Evolution, University of Lausanne, 1015 Lausanne, Switzerland.
SIB Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland.
Gigascience. 2024 Jan 2;13. doi: 10.1093/gigascience/giae054.
Research on animal venoms and their components spans multiple disciplines, including biology, biochemistry, bioinformatics, pharmacology, medicine, and more. Manipulating and analyzing the diverse array of data required for venom research can be challenging, and relevant tools and resources are often dispersed across different online platforms, making them less accessible to nonexperts. In this article, we address the multifaceted needs of the scientific community involved in venom and toxin-related research by identifying and discussing web resources, databases, and tools commonly used in this field. We have compiled these resources into a comprehensive table available on the VenomZone website (https://venomzone.expasy.org/10897). Furthermore, we highlight the challenges currently faced by researchers in accessing and using these resources and emphasize the importance of community-driven interdisciplinary approaches. We conclude by underscoring the significance of enhancing standards, promoting interoperability, and encouraging data and method sharing within the venom research community.
对动物毒液及其成分的研究跨越多个学科，包括生物学、生物化学、生物信息学、药理学、医学等。处理和分析毒液研究所需的多样化数据可能具有挑战性，相关工具和资源通常分散在不同的在线平台上，这使得非专业人士难以获取。在本文中，我们通过确定和讨论该领域常用的网络资源、数据库和工具，来满足参与毒液和毒素相关研究的科学界的多方面需求。我们将这些资源汇编到一个综合表格中，并在 VenomZone 网站（https://venomzone.expasy.org/10897）上提供。此外，我们还强调了研究人员在访问和使用这些资源时所面临的挑战，并强调了社区驱动的跨学科方法的重要性。最后，我们强调了提高毒液研究界标准、促进互操作性以及鼓励数据和方法共享的重要性。
