Department of Pediatric and Preventive Dentistry, ITS - CDSR, Ghaziabad, Uttar Pradesh, India.
J Indian Soc Pedod Prev Dent. 2024 Jul 1;42(3):203-210. doi: 10.4103/jisppd.jisppd_214_24. Epub 2024 Sep 9.
Bacteria and their byproducts are key contributors to the onset and perpetuation of pulpoperiapical pathosis. Intracanal medication is vital in achieving successful endodontic outcomes as it targets and eradicates remaining microorganisms following biomechanical preparation.
The aim of the study was to compare and evaluate the antimicrobial efficacy of calcium hydroxide (CH) paste, triple antibiotic paste (TAP), and probiotics (PBs) as intracanal medicament in 12-17-year-old children undergoing root canal treatment for the management of infected pulpal tissues in young permanent teeth.
A total of 30 patients aged 12-17 years indicated for endodontic therapy in maxillary incisors and with no systemic complications were selected. They were randomly divided into three groups, i.e., Group I - CH group, Group II - TAP, and Group III - PB allocating 10 teeth in each group. After access opening, the first sample (S1) was collected by inserting a paper point into the root canal, the second sample (S2) was collected immediately after biomechanical preparation, and the third sample (S3) was collected after 7 days, i.e., postintracanal medication. Samples were sent for microbiological analysis to assess the microbial count, and statistical analysis was done for the obtained data.
The three intracanal medicaments were successful in reducing the microbial counts of Enterococcus faecalis in the infected root canals. However, according to the results of the study, the PB group demonstrated greater effectiveness against E. faecalis compared to the CH group and displayed similar antimicrobial efficacy as the TAP group.
PB exhibited antimicrobial efficacy comparable to TAP but greater than Ca (OH) 2 paste. Hence, PB can be utilized as an intracanal medicament in young permanent teeth.
细菌及其产物是牙髓根尖病变发生和持续的关键因素。根管内用药对于实现成功的根管治疗结果至关重要,因为它可以在生物力学预备后靶向并消除残留的微生物。
本研究旨在比较和评估氢氧化钙(CH)糊剂、三抗糊剂(TAP)和益生菌(PBs)作为 12-17 岁儿童根管治疗中用于感染牙髓组织管理的根管内药物的抗菌效果。
选择了 30 名年龄在 12-17 岁、患有上颌切牙、无全身并发症的患者,需要进行根管治疗。他们被随机分为三组,即 I 组-CH 组、II 组-TAP 组和 III 组-PB 组,每组 10 颗牙齿。打开入口后,通过将纸尖插入根管中采集第一个样本(S1),立即在生物力学预备后采集第二个样本(S2),在 7 天后即根管内用药后采集第三个样本(S3)。将样本送去进行微生物分析,以评估微生物计数,然后对获得的数据进行统计分析。
三种根管内药物都成功地减少了感染根管中粪肠球菌的微生物数量。然而,根据研究结果,与 CH 组相比,PB 组对粪肠球菌的效果更好,并且与 TAP 组的抗菌效果相似。
PB 表现出与 TAP 相当的抗菌效果,但优于 Ca(OH)2 糊剂。因此,PB 可以在年轻的恒牙中用作根管内药物。