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参与“送餐上门”项目的老年受试者的营养评估与补充

Nutritional evaluation and supplementation of elderly subjects participating in a "meals on wheels" program.

作者信息

Lipschitz D A, Mitchell C O, Steele R W, Milton K Y

出版信息

JPEN J Parenter Enteral Nutr. 1985 May-Jun;9(3):343-7. doi: 10.1177/0148607185009003343.

Abstract

A nutritional assessment of 33 elderly subjects participating in a "meals on wheels" program revealed a high prevalence of nutritional deficiencies. Twelve of these subjects, who were considered to be at high risk for protein calorie malnutrition, received 240 ml of a polymeric dietary supplement three times daily for 16 wk. This resulted in a significant (50%) increase in total caloric and protein intake which was maintained for the entire 16 wk of study. In seven of the 12 subjects a weight gain of greater than 2 kg was found. Modest but significant elevations in serum albumin and highly significant elevations of the total iron binding capacity, serum and red cell folate, leukocyte ascorbate, and serum vitamin B12 provided strong evidence for improved nutritional status. In contrast no improvement in the hemoglobin, total lymphocyte count, T cell number, T suppressor cells, T helper, or B cells was noted. In no anergic subjects was skin test conversion found. In addition no increase in serum trace metals or vitamin B6 levels were noted. Thus this study demonstrates that nutritional supplementation results in significant improvement in selected nutritional parameters. The fact that the hematopoietic and immunological status of these patients was unchanged suggest that the abnormalities may be age rather than nutritionally related or that a critical nutritional deficiency was not corrected.

摘要

对33名参与“送餐上门”项目的老年受试者进行的营养评估显示,营养缺乏的患病率很高。其中12名被认为有蛋白质热量营养不良高风险的受试者,每天三次接受240毫升聚合膳食补充剂,持续16周。这导致总热量和蛋白质摄入量显著增加(50%),并在整个16周的研究中保持。在12名受试者中的7名中,体重增加超过2千克。血清白蛋白适度但显著升高,总铁结合力、血清和红细胞叶酸、白细胞维生素C和血清维生素B12高度显著升高,为营养状况改善提供了有力证据。相比之下,血红蛋白、总淋巴细胞计数、T细胞数量、T抑制细胞、T辅助细胞或B细胞没有改善。在无反应性受试者中未发现皮肤试验转阴。此外,血清微量金属或维生素B6水平没有升高。因此,本研究表明营养补充可使选定的营养参数显著改善。这些患者的造血和免疫状态未改变这一事实表明,异常情况可能与年龄而非营养有关,或者关键的营养缺乏未得到纠正。

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