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影响最罕见胸部恶性肿瘤的最新治疗策略:双向性胸膜间皮瘤的临床病例报告

Newest therapeutic strategies impacting on rarest thoracic malignancies: The clinical case report of biphasic pleural mesothelioma.

作者信息

Pellicioli F, Sala L, Colonese F, Belloni E, Abbate M I, Canova S, D'Agostino A, Cortinovis D L

机构信息

CS Medical Oncology, IRCCS San Gerardo Dei Tintori Foundation, Monza, Italy.

Department of Medical-Surgical Specialties, University of Brescia, Radiological Sciences and Public Health, Brescia, Italy.

出版信息

Heliyon. 2024 Aug 14;10(16):e36306. doi: 10.1016/j.heliyon.2024.e36306. eCollection 2024 Aug 30.

Abstract

A caucasian 62-year-old woman, diagnosed with biphasic pleural mesothelioma (PM) of II stage and BAP1 loss, was treated with therapies included in clinical trial and Early Access Programmes (EAP). During her clinical history, radiological images presented an unusual representation of the disease, with a pseudo progression discussed many times by several specialists. The patient's overall survival improved as a result of the multidisciplinary team and the availability of medicines outside of clinical practice.

摘要

一名62岁的白种女性,被诊断为II期双相性胸膜间皮瘤(PM)且存在BAP1缺失,接受了临床试验和早期准入计划(EAP)中包含的治疗。在其临床病程中,影像学图像呈现出该疾病的异常表现,多位专家多次讨论了假性进展情况。由于多学科团队的努力以及临床实践之外药物的可及性,患者的总生存期得到了改善。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a7b0/11382305/902bad53adff/gr1.jpg

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