An easily constructed durable chronic intracerebral cannula system.

A simple, inexpensive, and rugged intracerebral cannula system is described and construction details are provided for both guide and injection cannula assemblies. The guide cannula assembly is easily and quickly molded from dental acrylic cement and has a protective acrylic collar surrounding the end of the actual guide cannula. This system is believed to offer some advantage over current methodologies in terms of expense, durability and ease of construction and is well suited to use in rodents.