Haning R V, Steinetz B, Weiss G
Obstet Gynecol. 1985 Jul;66(1):42-5.
The serum relaxin and human chorionic gonadotropin (hCG) concentrations were determined in 17 spontaneous singleton pregnancies and four singleton pregnancies and five multiple gestations that followed treatment with menotropins. The geometric mean serum relaxin concentrations for the control and postmenotropins singleton pregnancies were similar (both 1.13 ng/mL), but the geometric mean serum relaxin concentration for multiple gestations that followed treatment with menotropins was significantly higher (2.56 ng/mL, P less than .01). A significant regression of serum relaxin on either days from the last menstrual period or serum hCG concentration was demonstrated. Covariance analysis supported the conclusion that multiple gestation produced a significant increase in serum relaxin concentration.
测定了17例自然单胎妊娠以及4例单胎妊娠和5例接受促性腺激素治疗后的多胎妊娠的血清松弛素和人绒毛膜促性腺激素（hCG）浓度。对照组和促性腺激素治疗后的单胎妊娠的血清松弛素几何平均浓度相似（均为1.13 ng/mL），但接受促性腺激素治疗后的多胎妊娠的血清松弛素几何平均浓度显著更高（2.56 ng/mL，P<0.01）。血清松弛素与末次月经日期或血清hCG浓度之间存在显著回归关系。协方差分析支持多胎妊娠导致血清松弛素浓度显著升高这一结论。
