Alamri Abdullah A, Amoodi Hosam A, Alsubaie Shahad A, Alsehly Areej A, Alshuaibi Razan O, Alotaibi Leena A, Almaghrabi Sahar J, Mozahim Sarah F, Mozahim Naif F, Tonkal Albaraa
Department of Otolaryngology, Head and Neck Surgery, King Abdulaziz University Hospital, Jeddah, Saudi Arabia.
Department of Otolaryngology, Head and Neck Surgery, Jeddah University, Jeddah, Saudi Arabia.
Afr J Paediatr Surg. 2024 Oct 1;21(4):236-241. doi: 10.4103/ajps.ajps_144_22. Epub 2024 Sep 7.
This systematic review and meta-analysis aimed to investigate the current evidence on the efficacy of tympanostomy and adenoidectomy in children with otitis media with effusion in comparison with tympanostomy alone following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement.
We completed a comprehensive search of PubMed, Web of Science, Scopus and Cochrane Library databases for relevant studies published in the literature with no date restrictions. We collected the results of the databases search and removed duplicated studies by Rayyan QCRI and EndNote Software X8. We used an Excel sheet for screening titles and abstracts, full text and data extraction. For quality assessment, we used Cochrane Handbook of Systematic Reviews of Interventions 5.1.0 using the quality assessment table provided in Part 2 and Chapter 8.5, and quantitative data synthesis was done using Review Manager (RevMan) software version 5.4.
The literature search showed 1510 studies, of which five studies were included in data synthesis. The study measured the effect through number of acute otitis media (AOM) episodes, cumulative number of AOM episodes, siblings with Otitis media (OM), hearing level hearing loss scale of the left, and right ears. The pooled effect estimates showed significant difference between tympanostomy with adenoidectomy versus tympanostomy alone in hearing level hearing loss scale of both ears (SMD -0.17, 95% CI [-0.29, -0.05], P -value=0.005). However, the pooled results were not heterogeneous ( P < 0.25, I2 = 24%).
Tympanostomy with adenoidectomy improves hearing compared to tympanostomy alone, but both treatments have similar effects on ear infection rates. Further research with larger samples is needed to confirm these findings and assess long-term benefits.
本系统评价和荟萃分析旨在根据系统评价和荟萃分析的首选报告项目声明，调查鼓膜切开术和腺样体切除术治疗儿童分泌性中耳炎与单纯鼓膜切开术相比的当前疗效证据。
我们对PubMed、科学网、Scopus和Cochrane图书馆数据库进行了全面检索，以查找文献中发表的无日期限制的相关研究。我们收集了数据库检索结果，并通过Rayyan QCRI和EndNote软件X8去除重复研究。我们使用Excel工作表筛选标题和摘要、全文并进行数据提取。对于质量评估，我们使用《Cochrane干预措施系统评价手册》5.1.0，采用第2部分和第8.5章提供的质量评估表，并使用Review Manager（RevMan）软件版本5.4进行定量数据合成。
文献检索显示有1510项研究，其中五项研究纳入了数据合成。该研究通过急性中耳炎（AOM）发作次数、AOM发作累计次数、患中耳炎（OM）的兄弟姐妹数量、左耳和右耳的听力水平听力损失量表来衡量效果。汇总效应估计显示，在双耳听力水平听力损失量表方面，鼓膜切开术联合腺样体切除术与单纯鼓膜切开术之间存在显著差异（标准化均数差为-0.17，95%置信区间[-0.29，-0.05]，P值=0.005）。然而，汇总结果不存在异质性（P<0.25，I²=24%）。
与单纯鼓膜切开术相比，鼓膜切开术联合腺样体切除术可改善听力，但两种治疗方法对耳部感染率的影响相似。需要进一步进行更大样本量的研究来证实这些发现并评估长期益处。
