Wedderburn N, Mitchell G H, Davies D R
Parasitology. 1985 Jun;90 ( Pt 3):573-8. doi: 10.1017/s0031182000055566.
Chronic quartan malarial infection has been established in the common marmoset (Callithrix jacchus). Plasmodium brasilianum from a douroucouli monkey (Aotus trivirgatus) was used to infect splenectomized twin animals, passed to an intact animal, and then to 4 other intact adults, 2 pairs of twins. In 2 of the 4 latter animals there was continuing patency with parasitaemias of less than or equal to 0.5% parasitized erythrocytes for 30 weeks. The other 2 had lower initial levels of parasitaemia; in 1 of these parasitaemias remained low or subpatent. All marmosets developed lymphocytosis. One animal became ill 30 weeks after infection with anaemia, weight loss and mild proteinurea, the other 3 remained well. Histological examination showed minor changes in the kidneys; spleens of infected animals showed marked follicular hyperplasia and phagocytosis of pigment. The livers showed sinusoidal hypercellularity and pigment deposition and in splenectomized animals, a marked lymphoid follicular hyperplasia in the portal tracts.
普通狨猴（Callithrix jacchus）已建立慢性三日疟感染。来自夜猴（Aotus trivirgatus）的巴西疟原虫被用于感染脾切除的孪生动物，再传给一只未切除脾脏的动物，然后传给另外4只未切除脾脏的成年动物，即2对孪生动物。在后面4只动物中的2只，寄生虫血症持续存在，被寄生红细胞的比例小于或等于0.5%，持续30周。另外2只动物最初的寄生虫血症水平较低；其中1只的寄生虫血症一直很低或处于隐性感染状态。所有狨猴都出现了淋巴细胞增多症。1只动物在感染30周后生病，出现贫血、体重减轻和轻度蛋白尿，另外3只情况良好。组织学检查显示肾脏有轻微变化；感染动物的脾脏显示出明显的滤泡增生和色素吞噬现象。肝脏显示出窦状隙细胞增多和色素沉积，在脾切除的动物中，门静脉区有明显的淋巴滤泡增生。
