Children's Hospital Los Angeles, Division of Cardiology, Keck School of Medicine of USC, Los Angeles, California, USA.
Curr Opin Pediatr. 2024 Oct 1;36(5):512-518. doi: 10.1097/MOP.0000000000001394. Epub 2024 Aug 16.
Speckle tracking echocardiography (STE)-derived measures of myocardial mechanics, referred to herewithin as strain measurements, directly assess myocardial contractility and provide a nuanced assessment of ventricular function. This review provides an overview of strain measurements and their current clinical value and utility in decision making in pediatric cardiology.
Strain measurements are advancing understanding of how cardiac dysfunction occurs in children with acquired and congenital heart disease (CHD). Global strain measurements can detect early changes in cardiac function and are reliable methods of serially monitoring systolic function in children. Global strain measurements are increasingly reported in echocardiographic assessment of ventricular function alongside ejection fraction. Research is increasingly focused on how strain measurements can help improve clinical management, risk stratification, and prognostic insight. Although more research is needed, preliminary studies provide hope that there will be clinical benefit for strain in pediatric cardiology management.
Strain measurements provide a more detailed assessment of ventricular function than conventional measures of echocardiographic functional assessment. Strain measurements are increasingly being used to advance understanding of normal and abnormal myocardial contractility, to increase sensitivity to detect early cardiac dysfunction, and to improve prognostic management in children with acquired and CHD.
斑点追踪超声心动图(STE)衍生的心肌力学测量值,本文中称为应变测量值,可直接评估心肌收缩力,并提供对心室功能的细致评估。本综述概述了应变测量值及其在儿科心脏病学中的临床价值和应用,为决策提供依据。
应变测量值加深了我们对获得性和先天性心脏病(CHD)患儿心脏功能障碍发生机制的理解。整体应变测量值可早期检测心脏功能变化,是儿童收缩功能连续监测的可靠方法。整体应变测量值在评估心室功能时与射血分数一起,越来越多地被用于超声心动图检查。研究越来越关注应变测量值如何帮助改善临床管理、风险分层和预后评估。尽管还需要更多的研究,但初步研究表明,应变在儿科心脏病学管理方面可能具有临床获益。
应变测量值比传统的超声心动图功能评估方法更详细地评估心室功能。应变测量值越来越多地被用于深入了解正常和异常心肌收缩力,提高早期心脏功能障碍的检测灵敏度,并改善获得性心脏病和 CHD 患儿的预后管理。