Department of Neurosurgery, University of Pennsylvania, 3400 Civic Center Blvd, Philadelphia, PA, 19104, USA.
Neurosurg Rev. 2024 Sep 11;47(1):588. doi: 10.1007/s10143-024-02860-9.
The author wished to detail the life and contributions of Dr. Adelola Adeloye, MBBS, MS, FWCS, FRCS, FACS, FRCP, in hope to pay homage to this giant in Global Neurosurgery. Dr. Adelola Adeloye was born on July 18, 1935 in Illesa, Osun State, present-day South-West Nigeria. The Adeloye-Odeku disease is an eponym for a congenital dermoid or epidermoid inclusion cyst (CDIC/CEDIC) over the anterior fontanelle and below the galea aponeurotica. In 1971, Adeloye and Odeku first described these cysts in 18 Nigerian patients. While overall rare and predominantly noted in children, the Adeloye-Odeku disease has been found to impact adults too. In terms of rarity, CDICs make up 0.1-0.5% of cranial tumors and 0.2% of inclusion cysts. CDICs can be distinguished from CEDICs through histopathology as dermoid cysts may contain hair follicles, sweat, sebaceous glands, and teeth, whereas CEDICs usually are only composed of keratinized debris and epidermal tissue. Assumed first to be an African cyst, cases of the Adeloye-Odeku disease were subsequently reported in other ethnic populations: Turkish, Czechs, Slovaks, Chinese, Japanese, Canadians, Saudi Arabians, Indians, Caucasians, Bangladeshis, Spaniards, and Brazilians.
作者希望详细介绍 Adelola Adeloye 医学博士、医学硕士、FWCS、FRCS、FACS、FRCP 的生平和贡献，以此向这位全球神经外科学领域的巨人致敬。Adelola Adeloye 博士于 1935 年 7 月 18 日出生在尼日利亚西南部的埃莱萨。阿德拉约-奥德库病是以其发现者的名字命名的，是一种发生在前囟门和腱膜下骨之间的先天性皮样或表皮样包涵囊肿（CDIC/CEDIC）。1971 年，Adeloye 和 Odeku 首次在 18 名尼日利亚患者中描述了这些囊肿。虽然这种疾病总体上较为罕见，主要发生在儿童中，但也有成年人发病的报道。从罕见程度来看，CDIC 占颅内肿瘤的 0.1-0.5%，占包涵囊肿的 0.2%。CDIC 可以通过组织病理学与 CEDIC 区分开来，因为皮样囊肿可能含有毛囊、汗腺、皮脂腺和牙齿，而 CEDIC 通常仅由角化碎片和表皮组织组成。起初被认为是一种非洲囊肿，随后在其他种族人群中也有报道了阿德拉约-奥德库病的病例：土耳其人、捷克人、斯洛伐克人、中国人、日本人、加拿大人、沙特阿拉伯人、印度人、高加索人、孟加拉人、西班牙人和巴西人。
