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便携式多导睡眠监测仪(Somnocheck micro CARDIO)可在有阻塞性睡眠呼吸暂停风险的精神科患者中提供准确的诊断信息:一项观察性队列研究。

Portable polygraphic device (Somnocheck micro CARDIO) provides accurate diagnostic information in psychiatric patients at risk for obstructive sleep apnoea: an observational cohort study.

机构信息

Department of Psychiatry and Psychotherapy, Friedrich-Alexander-Universität Erlangen-Nürnberg, Schwabachanlage 6, 91054, Erlangen, Germany.

Department of Neurology, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.

出版信息

BMC Psychiatry. 2024 Sep 10;24(1):607. doi: 10.1186/s12888-024-06049-8.

Abstract

BACKGROUND

Symptoms of obstructive sleep apnoea (OSA) overlap significantly with those of psychiatric disorders, making accurate diagnosis of OSA challenging within psychiatric settings. Diagnosing OSA in psychiatric patients is crucial because untreated OSA can exacerbate psychiatric symptoms, reduce treatment efficacy, and impair overall quality of life. This study aimed to determine the diagnostic accuracy of a readily accessible procedure for psychiatric patients in a real-world clinical setting by comparing the Somnocheck micro CARDIO (SCm) portable cardiorespiratory polygraphy device with the gold standard polysomnography (PSG).

METHODS

This observational cohort study included consecutive psychiatric patients at intermediate to high risk for OSA based on screening with the STOP-Bang questionnaire, admitted to a single tertiary care centre between June 1, 2016 and December 31, 2022. The Apnoea-Hypopnoea-Index (AHI), Apnoea-Index (AI), Oxygen-Desaturation-Index (ODI), and minimum oxygen saturation were measured sequentially by SCm and PSG.

RESULTS

A total of 57 patients were analysed (median age 62.0 [Interquartile Range (IQR), 51.5-72.5] years; 34 [59.6%] men). Regarding AHI, no significant differences (AHI measured by PSG, median, 16.6 [IQR, 6.2-26.7] vs. AHI measured by SCm, median, 14.9 [IQR, 10.0-22.8]; p = 0.812; r = 0.71) were found between SCm and PSG. AI, ODI and minimum oxygen saturation differed significantly between SCm and PSG. Using optimised cut-off values (any OSA: AHI ≥ 9.25), SCm showed high sensitivity (0.894) and high specificity (0.800) for the diagnosis of OSA, with an area under the receiver operating characteristic curve of 0.877.

CONCLUSIONS

This study found that the SCm portable device was accurate in identifying psychiatric patients with OSA. AHI measurement by SCm provided reliable diagnostic performance in comparison with the gold standard polysomnography. These findings support the integration of polygraphic measurements into the routine sleep assessment of psychiatric patients. Early and accurate diagnosis of OSA in this population can significantly improve the management of both sleep disorders and psychiatric conditions, potentially enhancing overall treatment outcomes and quality of life for these patients.

摘要

背景

阻塞性睡眠呼吸暂停(OSA)的症状与精神障碍的症状有很大的重叠,因此在精神科环境中准确诊断 OSA 具有挑战性。在精神科患者中诊断 OSA 至关重要,因为未经治疗的 OSA 会加重精神症状、降低治疗效果并损害整体生活质量。本研究旨在通过比较 Somnocheck 微 CARDIO(SCm)便携式心肺多导睡眠图设备与金标准多导睡眠图(PSG),确定一种在现实临床环境中易于获得的程序在精神科患者中的诊断准确性。

方法

本观察性队列研究纳入了 2016 年 6 月 1 日至 2022 年 12 月 31 日期间在一家三级护理中心因筛查量表(STOP-Bang 问卷)而被认为是中高危 OSA 的连续精神科患者。依次使用 SCm 和 PSG 测量呼吸暂停-低通气指数(AHI)、呼吸暂停指数(AI)、氧减饱和度指数(ODI)和最低血氧饱和度。

结果

共分析了 57 例患者(中位年龄 62.0[四分位距(IQR),51.5-72.5]岁;34[59.6%]名男性)。关于 AHI,PSG 测量的 AHI (中位数 16.6[IQR,6.2-26.7])与 SCm 测量的 AHI (中位数 14.9[IQR,10.0-22.8])之间无显著差异(p=0.812;r=0.71)。AI、ODI 和最低血氧饱和度在 SCm 和 PSG 之间存在显著差异。使用优化的截断值(任何 OSA:AHI≥9.25),SCm 对 OSA 的诊断具有高灵敏度(0.894)和高特异性(0.800),受试者工作特征曲线下面积为 0.877。

结论

本研究发现,SCm 便携式设备可准确识别患有 OSA 的精神科患者。与金标准多导睡眠图相比,SCm 测量的 AHI 提供了可靠的诊断性能。这些发现支持将多导睡眠图测量纳入精神科患者的常规睡眠评估。在该人群中早期和准确地诊断 OSA 可以显著改善睡眠障碍和精神疾病的管理,从而有可能提高这些患者的整体治疗效果和生活质量。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2c5f/11389046/37332f153ec2/12888_2024_6049_Fig1_HTML.jpg

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