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美国髋部骨折老年患者向社区护理过渡期间,阿片类药物处方在种族上的差异。

Differences in opioid prescriptions by race among U.S. older adults with a hip fracture transitioning to community care.

作者信息

Hayes Kaleen N, Cupp Meghan A, Joshi Richa, Riester Melissa R, Beaudoin Francesca L, Zullo Andrew R

机构信息

Department of Health Services, Policy, and Practice, Brown University School of Public Health, Providence, Rhode Island, USA.

Center for Gerontology and Healthcare Research, Brown University School of Public Health, Providence, Rhode Island, USA.

出版信息

J Am Geriatr Soc. 2024 Dec;72(12):3730-3741. doi: 10.1111/jgs.19160. Epub 2024 Sep 11.

Abstract

BACKGROUND

Appropriate pain management can facilitate rehabilitation after a hip fracture as patients transition back to the community setting. Differences in opioid prescribing by race may exist during this critical transition period.

METHODS

We conducted a retrospective cohort study of older adult U.S. Medicare beneficiaries with a hip fracture to examine whether the receipt and dose of opioids differs between Black and White patients as they transitioned back to the community setting. We stratified beneficiaries by whether they received institutional post-acute care (PAC). Outcomes were (1) receipt of an opioid and (2) opioid doses in the first 90 days in the community in milligram morphine equivalents (MMEs; also presented in mg oxycodone). We estimated relative rates and risk differences of opioid receipt and dose differences using Poisson and linear regression models, respectively, using the parametric g-formula to standardize for age and sex.

RESULTS

We identified 164,170 older adults with hip fracture (mean age = 82.7 years; 75% female; 72% with PAC; 46% with opioid use after fracture). Overall use of opioids in the community was similar between Black and white beneficiaries. Black beneficiaries had lower average doses in their first 90 days in both total cumulative doses (PAC group: 165 [95% CI -264 to -69] fewer MMEs [-248 mg oxycodone]; no PAC: 167 [95% CI -274 to -62] fewer MMEs [-251 mg oxycodone]) and average MME per days' supply of medication (PAC: -3.0 [-4.6 to -1.4] fewer MMEs per day [-4.5 mg oxycodone]; no PAC: -4.7 [-4.6 to -1.4] fewer MMEs per day [-7.1 mg oxycodone]). In secondary analyses, Asian beneficiaries experienced the greatest differences (e.g., 617-653 fewer cumulative mg oxycodone).

CONCLUSION

Racial differences exist in pain management for Medicare beneficiaries after a hip fracture. Future work should examine whether these differences result in disparities in short- and long-term health outcomes.

摘要

背景

在患者向社区环境过渡期间,适当的疼痛管理有助于髋部骨折后的康复。在这个关键的过渡阶段,按种族划分的阿片类药物处方可能存在差异。

方法

我们对美国医疗保险老年受益人中的髋部骨折患者进行了一项回顾性队列研究,以检查黑人和白人患者在向社区环境过渡时阿片类药物的使用情况和剂量是否存在差异。我们根据是否接受机构急性后护理(PAC)对受益人进行分层。结果包括:(1)阿片类药物的使用情况;(2)社区环境中前90天内以毫克吗啡当量(MME;也以毫克羟考酮表示)计算的阿片类药物剂量。我们分别使用泊松回归模型和线性回归模型估计阿片类药物使用情况的相对率和风险差异以及剂量差异,并使用参数化g公式对年龄和性别进行标准化。

结果

我们确定了164,170名髋部骨折的老年人(平均年龄 = 82.7岁;75%为女性;72%接受PAC;46%骨折后使用阿片类药物)。黑人和白人受益人在社区中阿片类药物的总体使用情况相似。黑人受益人在前90天内的平均剂量较低,无论是总累积剂量(PAC组:少165[95%CI -264至-69]毫克吗啡当量[-248毫克羟考酮];无PAC组:少167[95%CI -274至-62]毫克吗啡当量[-251毫克羟考酮])还是每天药物供应的平均吗啡当量(PAC组:每天少3.0[-4.6至-1.4]毫克吗啡当量[-4.5毫克羟考酮];无PAC组:每天少4.7[-4.6至-1.4]毫克吗啡当量[-7.1毫克羟考酮])。在二次分析中,亚洲受益人经历的差异最大(例如,累积羟考酮毫克数少617 - 653)。

结论

医疗保险受益人髋部骨折后的疼痛管理存在种族差异。未来的工作应研究这些差异是否会导致短期和长期健康结果的差异。

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Concerns for Older Adult Patients with Acute Hip Fracture.对老年急性髋部骨折患者的关注。
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