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用于食物过敏个体的肾上腺素自动注射器:适用人群、使用数量及使用时机。

Epinephrine autoinjectors for individuals with food allergy: Who, how many, and when to use.

作者信息

Wang Julie

机构信息

From the Division of Allergy and Immunology, Department of Pediatrics, Jaffe Food Allergy Institute, Icahn School of Medicine at Mount Sinai, New York, New York.

出版信息

J Food Allergy. 2024 Jul 1;6(1):32-36. doi: 10.2500/jfa.2024.6.240004. eCollection 2024 Jul.

Abstract

BACKGROUND

Anaphylaxis is a serious allergic reaction that is effectively treated with epinephrine. Epinephrine autoinjectors are devices that contain fixed doses of medication that can be carried by patients at risk for anaphylaxis so that ready access to first line medication is available outside the medical setting.

METHODS

This review will discuss recent studies evaluating patient characteristics to consider when prescribing epinephrine autoinjectors.

RESULTS

Decisions regarding who should be prescribed epinephrine autoinjectors will depend on the type of allergy, as well as co-morbidities and other risk factors that can increase a patient's risk for poor outcomes.

CONCLUSION

Shared decision-making is essential when developing guidance regarding post-epinephrine management. Regular education during routine follow-up visits can reinforce knowledge and skills for managing food allergy reactions.

摘要

背景

过敏反应是一种严重的过敏反应,可用肾上腺素有效治疗。肾上腺素自动注射器是一种装有固定剂量药物的装置,有过敏反应风险的患者可以携带,以便在医疗机构外能够随时获取一线药物。

方法

本综述将讨论近期评估在开具肾上腺素自动注射器处方时应考虑的患者特征的研究。

结果

关于谁应该开具肾上腺素自动注射器的决定将取决于过敏类型,以及可能增加患者不良结局风险的合并症和其他风险因素。

结论

在制定肾上腺素使用后管理指南时,共同决策至关重要。在常规随访期间进行定期教育可以强化管理食物过敏反应的知识和技能。

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本文引用的文献

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Anaphylaxis: A 2023 practice parameter update.过敏反应:2023 年实践参数更新。
Ann Allergy Asthma Immunol. 2024 Feb;132(2):124-176. doi: 10.1016/j.anai.2023.09.015. Epub 2023 Dec 18.
2
Factors Associated With Epinephrine Use in the Treatment of Anaphylaxis in Infants and Toddlers.与使用肾上腺素治疗婴幼儿过敏反应相关的因素
J Allergy Clin Immunol Pract. 2024 Feb;12(2):364-371.e1. doi: 10.1016/j.jaip.2023.10.049. Epub 2023 Nov 2.
3
Innovations in the treatment of anaphylaxis: A review of recent data.过敏反应治疗的创新:近期数据回顾。
Ann Allergy Asthma Immunol. 2023 Aug;131(2):185-193.e10. doi: 10.1016/j.anai.2023.05.033. Epub 2023 Jun 4.
4
Who Needs Epinephrine? Anaphylaxis, Autoinjectors, and Parachutes.谁需要肾上腺素?过敏反应、自动注射器和降落伞。
J Allergy Clin Immunol Pract. 2023 Apr;11(4):1036-1046. doi: 10.1016/j.jaip.2023.02.002. Epub 2023 Feb 14.
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Acute At-Home Management of Anaphylaxis: 911: What Is the Emergency?急性家中过敏反应处理:911:这是紧急情况吗?
J Allergy Clin Immunol Pract. 2022 Sep;10(9):2274-2279. doi: 10.1016/j.jaip.2022.04.040. Epub 2022 May 13.
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Allergy. 2022 Feb;77(2):357-377. doi: 10.1111/all.15032. Epub 2021 Sep 1.
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Acute At Home Management of Anaphylaxis During the Covid-19 Pandemic.新冠疫情期间过敏性反应的急性居家管理
J Allergy Clin Immunol Pract. 2020 Jun;8(6):1795-1797. doi: 10.1016/j.jaip.2020.04.022. Epub 2020 Apr 18.

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