A systematic review of ticks and tick-borne pathogens of cattle reared by smallholder farmers in South Africa.

Ticks are important ectoparasites of domestic animals, wild animals and humans. They spread a variety of infective agents such as protozoans, viruses, and bacteria. Cattle reared by smallholder farmers are susceptible to ticks and tick-borne pathogens due to the type of production system practiced by the farmers. Hence, this review was focused on the occurrence of ticks and tick-borne pathogens in cattle reared by smallholder farmers in South Africa. The systematic search produced a total of 13,408 articles from four databases, and after screening processes, the review utilized 23 articles published between 1983 and 2023. A total of 26 tick species belonging to seven genera were identified in the reviewed articles, with () and being the most frequently reported tick species in South Africa followed by , , , , , and . The most frequently reported tick-borne pathogens across the provinces included , , and , with Eastern Cape Province accounting for most of the records followed by KwaZulu-Natal and Mpumalanga Provinces. The findings of this review confirm that cattle reared by smallholder farmers harbour various ticks and tick-borne pathogens of veterinary, public health and economic importance, and regular monitoring of tick infestations in South Africa is recommended to avoid disease outbreaks.