Merveille C, Baeckeland E, Renard A M
Ann N Y Acad Sci. 1985;442:80-7. doi: 10.1111/j.1749-6632.1985.tb37507.x.
Oocytes removed from antral follicles of 28- to 30-day-old rats treated with FSH (Folligon) show cavities and vesicles in the nucleoli. Repeated injections of Folligon significantly increase the frequency of these nucleolar inclusions. A possible relationship between intranucleolar cavities and rRNA metabolism has been suggested to account for this occurrence.
从用促卵泡素(Folligon)处理的28至30日龄大鼠的窦状卵泡中取出的卵母细胞,其核仁中可见空洞和小泡。重复注射促卵泡素会显著增加这些核仁内含物的出现频率。有人提出核仁内空洞与核糖体RNA代谢之间可能存在关联,以此来解释这种现象的发生。