Csaba G, Madarász B
Department of Biology, Semmelweis University of Medicine, Budapest, Hungary.
Cytobios. 1993;74(296):7-14.
In the ovaries of newborn rats the exogenous follicle stimulating hormone (FSH) given in a large dose leads to the appearance of uncommon structures in the nucleoli of the oocytes. Fuzzy filaments sometimes with chiasma-like connections appear and ring-like structures in connection with, or independent of, the nucleoli are seen. The results demonstrate the possible appearance of a morphological response of oocytes to FSH prior to any detectable biochemical or receptor binding evidence.
在新生大鼠的卵巢中,大剂量给予外源性促卵泡激素(FSH)会导致卵母细胞核仁中出现不寻常的结构。有时会出现带有交叉样连接的模糊细丝,并且可以看到与核仁相关或独立于核仁的环状结构。结果表明,在任何可检测到的生化或受体结合证据之前,卵母细胞可能会出现对FSH的形态学反应。