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基于干细胞视角的卵巢早衰研究的全球文献计量学和可视化分析。

A global bibliometric and visual analysis of research on premature ovarian failure: Based on the perspective of stem cells.

机构信息

Department of Pharmaceutical Engineering, School of Life and Health Sciences, Huzhou College, Huzhou, Zhejiang Province, China.

School of Life Sciences and Technology, Tongji University, Shanghai, China.

出版信息

Medicine (Baltimore). 2024 May 31;103(22):e38399. doi: 10.1097/MD.0000000000038399.

Abstract

Premature ovarian failure (POF), a condition influenced by genetic and immune factors, remains incurable despite years of intensive research and significant efforts. This persisting challenge underscores the urgency to address this escalating health concern. Fortunately, stem cell regenerative medicine has emerged as a promising avenue for developing therapeutic strategies and innovative treatments for POF. Bibliometric analysis, renowned for its objectivity, systematic approach, and comprehensive coverage of a given field, has yet to be applied to the study of stem cell research in POF. This study used CiteSpace software to assess contributions and co-occurrence relationships among various countries/regions, institutes, journals, and authors. This approach also allowed us to identify research hotspots and promising future trends within this field. Additionally, we generated visualizing maps utilizing the Web of Science Core Collection (WOSCC) and PubMed publications. By providing valuable information and references, we aim to enhance the understanding of the challenges involved in translating stem cell regeneration into clinical therapeutic potential for POF. Furthermore, our analysis and findings guide researchers and clinicians, facilitating future collaborative research and clinical intervention efforts.

摘要

卵巢早衰(POF)是一种受遗传和免疫因素影响的疾病,尽管经过多年的深入研究和大量努力,仍然无法治愈。尽管取得了显著的进展,但这种持续存在的挑战突显了迫切需要解决这一日益严重的健康问题。幸运的是,干细胞再生医学已成为开发 POF 治疗策略和创新疗法的有前途的途径。文献计量分析以其客观性、系统性和对给定领域的全面覆盖而闻名,但尚未应用于 POF 中干细胞研究的研究。本研究使用 CiteSpace 软件评估了不同国家/地区、机构、期刊和作者之间的贡献和共现关系。这种方法还使我们能够识别该领域的研究热点和有前途的未来趋势。此外,我们还利用 Web of Science Core Collection(WOSCC)和 PubMed 出版物生成可视化图谱。通过提供有价值的信息和参考文献,我们旨在增强对将干细胞再生转化为 POF 临床治疗潜力所涉及的挑战的理解。此外,我们的分析和发现为研究人员和临床医生提供了指导,有助于未来的合作研究和临床干预工作。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8418/11142804/6ae0e12c68f1/medi-103-e38399-g001.jpg

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