Hossein Nakhaei, Mehdi Mogharnasi, Karim Dehghani, Mahdi Mohammadi, Ghasemi Elham
Health Promotion Research Center, Zahedan University of Medical Sciences, Zahedan, Iran.
Faculty of Sport Sciences, University of Birjand, Birjand, Iran.
Hormones (Athens). 2025 Mar;24(1):23-31. doi: 10.1007/s42000-024-00595-2. Epub 2024 Sep 11.
The present study aimed to investigate the effects of 8 weeks spirulina supplementation and circuit resistance training (CRT) on asprosin, appetite, and energy balance in men with obesity and overweight.
The study comprised a single-blind randomized controlled trial. Sixty men with obesity and overweight (BMI > 25) were selected and randomly divided into four equal groups (n = 15 each) of training plus spirulina, training plus placebo, spirulina, and placebo. The participants of the training groups performed 12 movements with 40-90% maximal repetition (three sessions per week) and the supplemental groups consumed 1000 mg of spirulina per day for 8 weeks. Asprosin, appetite using visual analog scales, calorie intake, energy expenditure, and body composition were measured before and after the intervention. To analyze the data, the paired sample t-test, analysis of covariance, Bonferroni post-hoc, and Pearson correlation tests were employed using SPSS (version 20) at a significance level of p < 0.05.
After the intervention, asprosin level (P = 0.015, P = 0.015, and P = 0.020, respectively), weight (P < 0.001, P < 0.001, and P < 0.001, respectively), calorie intake (P = 0.015, P = 0.011, and P = 0.004, respectively), and hunger (P = 0.011, P = 0.015, and P = 0.015, respectively) declined in the training plus spirulina, training plus placebo, and spirulina groups (p < 0.05). In addition, energy expenditure (P = 0.012 and P = 0.015, respectively) and fullness (P = 0.015 and P = 0.011, respectively) increased in the training plus spirulina and training plus placebo groups. The mean changes of the research indicators in the training plus spirulina group were significantly more than those of the other groups (p < 0.001).
It was shown that 8 weeks of CRT and spirulina supplementation decreases the level of asprosin and improves appetite and energy balance in men with obesity and overweight.
本研究旨在探讨补充8周螺旋藻和循环抗阻训练（CRT）对肥胖和超重男性的脂肪因子、食欲及能量平衡的影响。
本研究为单盲随机对照试验。选取60名肥胖和超重男性（BMI>25），随机分为四组，每组15人，分别为训练加螺旋藻组、训练加安慰剂组、螺旋藻组和安慰剂组。训练组参与者进行12个动作，重复次数为最大重复次数的40%-90%（每周3次），补充组每天服用1000毫克螺旋藻，持续8周。在干预前后测量脂肪因子、用视觉模拟量表评估的食欲、卡路里摄入量、能量消耗和身体成分。使用SPSS（20版）进行数据分析，采用配对样本t检验、协方差分析、Bonferroni事后检验和Pearson相关检验，显著性水平为p<0.05。
干预后，训练加螺旋藻组、训练加安慰剂组和螺旋藻组的脂肪因子水平（分别为P=0.015、P=0.015和P=0.020）、体重（分别为P<0.001、P<0.001和P<0.001）、卡路里摄入量（分别为P=0.015、P=0.011和P=0.004）和饥饿感（分别为P=0.011、P=0.015和P=0.015）均下降（p<0.05）。此外，训练加螺旋藻组和训练加安慰剂组的能量消耗（分别为P=0.012和P=0.01）和饱腹感（分别为P=0.015和P=0.011）增加。训练加螺旋藻组研究指标的平均变化显著大于其他组（p<0.001）。
结果表明，8周的CRT和螺旋藻补充可降低肥胖和超重男性的脂肪因子水平，改善食欲和能量平衡。
